# Analgesic Differences in Males and Females After Third Molar Surgery: A Subgroup Analysis of the OARS Randomized Clinical Trial

## TL;DR

This study examines how pain relief and treatment satisfaction differ between males and females after wisdom tooth surgery.

## Contribution

The study provides a gender-specific analysis of nonopioid versus opioid pain management effectiveness after third molar surgery.

## Key findings

- Nonopioids showed noninferior pain relief compared to opioids in both males and females.
- Patient satisfaction was comparable between nonopioid and opioid treatments in both genders.

## Abstract

This prespecified subgroup analysis of a randomized clinical trial investigates noninferiority for pain relief, treatment effects, and patient satisfaction for nonopioids vs opioids in male and female patients after impacted mandibular third molar extraction.