# Effectiveness of a forgiveness-based intervention to promote post-traumatic growth in hemodialysis patients: an experimental controlled study

**Authors:** Qin Xie, Yue Zhang, Yansheng Ye, Hong Wang, Dan Luo, Changwei Mu

PMC · DOI: 10.3389/fpsyg.2025.1680748 · Frontiers in Psychology · 2025-10-20

## TL;DR

A forgiveness-based program helped hemodialysis patients grow emotionally and reduce anxiety and depression, with benefits lasting three months.

## Contribution

First empirical evidence of a forgiveness-based intervention promoting post-traumatic growth in hemodialysis patients.

## Key findings

- The intervention significantly increased post-traumatic growth and forgiveness in hemodialysis patients.
- Anxiety, depression, and negative coping improved significantly in the intervention group.
- Benefits were maintained at a three-month follow-up.

## Abstract

Post-Traumatic Growth (PTG) is a key indicator of psychological wellbeing and quality of life in patients undergoing Maintenance Hemodialysis (MHD). Forgiveness, as a positive psychological process, involves transforming negative responses into adaptive ones after trauma and may facilitate PTG by reducing resentment and promoting emotional recovery. However, empirical evidence on the effectiveness of forgiveness-based interventions in enhancing PTG remains limited, particularly among hemodialysis patients.

This study aimed to develop a forgiveness-based intervention program for post-traumatic growth in patients undergoing MHD and to evaluate its effectiveness.

This study was conducted in a tertiary hospital in Yunnan Province with 78 maintenance hemodialysis patients assigned to an intervention group (n = 39) and a control group (n = 39). The intervention group received an 8 week nurse-delivered forgiveness-based psychological program alongside routine care, while the control group received routine care only. Post-traumatic growth, forgiveness, coping style, anxiety, depression, heart rate, and blood pressure were assessed at baseline, post-intervention, and 3 month follow-up. Data analysis was performed using descriptive statistics, independent t tests, chi-square or Fisher's exact tests, repeated-measures ANOVA, and paired t tests. Statistical significance was set at p < 0.05.

Both groups were comparable at baseline across all outcome measures. Post-traumatic growth significantly increased in the intervention group compared to the control group at the end of the intervention (T2: p < 0.001) and at three-month follow-up (T3: p < 0.001). Forgiveness scores were also significantly higher in the intervention group at both T2 and T3 (p < 0.001). Positive coping showed significant improvement at both time points (p < 0.001), while negative coping, anxiety, and depression scores were significantly reduced (all p < 0.01). No significant differences were found between groups in heart rate or blood pressure at any time point.

The forgiveness-based intervention program showed beneficial effects on post-traumatic growth, forgiveness, and emotional adjustment in patients receiving maintenance hemodialysis. As a low-cost approach, it has the potential to be incorporated into routine dialysis care to help promote post-traumatic growth in patients receiving maintenance hemodialysis.

https://www.chictr.org.cn/showproj.aspx?proj=184556, identifier Chinese Clinical Trial Registry (ChiCTR2200066914).

## Full-text entities

- **Diseases:** trauma (MESH:D014947), depression (MESH:D003866), anxiety (MESH:D001007)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

50 references — full list in the complete paper: https://tomesphere.com/paper/PMC12592882/full.md

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Source: https://tomesphere.com/paper/PMC12592882