# Eutocic delivery vs. cesarean section: a multicenter retrospective study of factors influencing cesarean rates in Robson groups 1, 2a, 3, and 4a across birth centers

**Authors:** Alessandra Musicco, Gianfranco Sfregola, Vincenzo Dicuonzo, Tatiana Bolgeo, Virginia Milone, Grazia Dicuonzo, Paolo Iovino, Federico Ruta

PMC · DOI: 10.3389/fmed.2025.1635018 · Frontiers in Medicine · 2025-10-24

## TL;DR

This study examines factors influencing cesarean section rates among different groups of women in Italy, finding that multiparity and spontaneous labor reduce the likelihood of a C-section.

## Contribution

The study provides new insights into how clinical factors like multiparity and labor induction affect cesarean delivery rates across different birth centers.

## Key findings

- Multiparous women are significantly less likely to undergo cesarean section compared to nulliparous women.
- Induced labor is associated with a fourfold increased likelihood of cesarean delivery compared to spontaneous labor.
- Significant variability in cesarean rates was observed across different birth centers for the same Robson groups.

## Abstract

Cesarean deliveries are increasing rapidly worldwide. Although their primary indication is when vaginal delivery is not feasible, there appears to be an overutilization of this procedure, even in the absence of clear medical or obstetric indications. This exposes women to short-term and long-term adverse outcomes. This study aimed to investigate factors associated with cesarean section (CS) in nulliparous and multiparous women undergoing spontaneous and induced labor, focusing on Robson groups 1, 2a, 3, and 4a in birth centers of the Apulia Region (Italy) in 2019.

This multicenter retrospective observational study used data from the Delivery Room Registers of 14 facilities in the Apulia Region in 2019, covering 14,331 women. Inclusion criteria were belonging to Robson groups 1, 2a, 3, or 4a. Exclusion criteria were stillbirths and deliveries occurring in ambulances or at home. The final sample consisted of 9,992 women. Multilevel binary logistic regression models were performed to assess the impact of Robson groups and their combinations on the likelihood of CS. Chi-squared and Fisher’s exact tests were used to examine the distribution of CS across facilities.

Among women with spontaneous labor, multiparity was protective against CS compared with nulliparity (OR = 0.44, p < 0.001). Similarly, in induced labor, multiparity remained protective (OR = 0.46, p < 0.001). Women undergoing induction were approximately four times more likely to deliver via CS compared with those in spontaneous labor (OR = 3.87, p < 0.001). Overall, multiparous women were substantially less likely to undergo CS compared with nulliparous women (OR = 0.18, p < 0.001). Significant variability in CS rates across facilities was observed for all Robson groups (p < 0.001).

Nulliparity and induction of labor were strongly associated with increased risk of CS. These factors should be carefully considered in clinical decision-making to help reduce unnecessary CS and mitigate associated adverse health outcomes.

## Full-text entities

- **Diseases:** stillbirths (MESH:D050497)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12592086/full.md

## References

39 references — full list in the complete paper: https://tomesphere.com/paper/PMC12592086/full.md

---
Source: https://tomesphere.com/paper/PMC12592086