# Effective management of large renal stones using retrograde intrarenal surgery with combined direct in-scope suction and flexible and navigable ureteral access sheath: a case report

**Authors:** Nadhif Faza Ananda, Karen Graciana Setiawan, Vindasya Almeira, Faiza Lavina Meutia, Favian Ariiq Rahmat, Armand Achmadsyah, Nur Rasyid, Widi Atmoko, Ponco Birowo

PMC · DOI: 10.3389/fruro.2025.1634754 · Frontiers in Urology · 2025-10-24

## TL;DR

This case report shows how combining RIRS with DISS and FANS can effectively remove large kidney stones with minimal invasiveness.

## Contribution

The novel integration of DISS and FANS with RIRS improves stone clearance and surgical efficiency for complex renal stones.

## Key findings

- A 96.2% stone-free rate was achieved after RIRS with DISS and FANS for a large staghorn stone.
- The technique maintained a clear surgical field and enabled real-time removal of stone fragments.
- The approach offers reduced operative challenges and improved outcomes for complex renal stones.

## Abstract

Managing large renal stones with minimally invasive techniques is challenging, particularly in achieving optimal stone clearance. This report highlights the use of Retrograde Intrarenal Surgery (RIRS) combined with Combined Direct In-Scope Suction (DISS), Flexible and Navigable Ureteral Access Sheath (FANS), and thulium laser as an innovative approach to managing a complex staghorn stone.

A 39-year-old male presented with left flank pain and hematuria for three weeks. Imaging revealed a large staghorn stone in the left kidney (2.8 x 1.5 x 4.3 cm, 1000–1200 HU) alongside smaller stones (0.5–1 cm) with associated grade II hydronephrosis and suspected ureterovesical junction stricture. RIRS was performed with a thulium laser and DISS and FANS to optimize visualization and enable efficient stone debris removal. Postoperative imaging revealed a single residual fragment (10 x 7 mm), resulting in a stone-free rate of 96.2%.

The integration of DISS and FANS in RIRS enhances procedural efficacy by maintaining a clear field of view and facilitating real-time removal of stone fragments. This approach proved to be effective in managing a large renal stone with minimal invasiveness, offering advantages such as reduced operative challenges and improved outcomes. This technique demonstrates the potential for RIRS as a viable alternative in selected scenarios.

RIRS combined with DISS and FANS represents a promising method for managing complex renal stones, achieving high stone-free rates with minimal complications.

## Linked entities

- **Diseases:** hydronephrosis (MONDO:0005510)

## Full-text entities

- **Diseases:** staghorn stone (MESH:D000069856), flank pain (MESH:D021501), renal stone (MESH:D007669), hematuria (MESH:D006417), ureterovesical junction stricture (MESH:D003251), hydronephrosis (MESH:D006869)

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12591867/full.md

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Source: https://tomesphere.com/paper/PMC12591867