# A modular library for fast prototyping of solution-state nuclear magnetic resonance experiments

## TL;DR

This paper introduces a modular library for creating and customizing NMR pulse sequences on Bruker spectrometers, enabling faster and more flexible experiment development.

## Contribution

The novel contribution is a two-level abstraction framework for pulse sequence development that reduces code duplication and enhances adaptability.

## Key findings

- The library supports switching between standard and TROSY variants of pulse programs.
- It allows seamless integration of real-time homodecoupling and hard or shaped pulses.
- A configurable 4D NOESY program demonstrates the library's adaptability.

## Abstract

We present a framework library (Modular Elements, ME) for the development of pulse sequences for Bruker spectrometers. It implements a two-level abstraction approach – the lower level comprises basic functional elements of pulse sequences and the higher one often-reused blocks comprising several evolution periods. The low-level abstractions reduce code duplication between variants of experiments such as hard-pulse and selective variants of individual NMR experiments. The high-level modules enable further reuse of pulse program code and aid in the construction of complex experiments. We show the library's functionality by presenting pulse programs that can be switched between standard and TROSY variants as well as hard and shaped pulses and that can seamlessly incorporate real-time homodecoupling. Adaptability is further demonstrated in a configurable 4D NOESY program.