# Early visual intervention, visual function analysis, and grating visual acuity outcomes in children with congenital Zika syndrome

**Authors:** Marcia Beatriz Tartarella, Ana Paula Braga, Jean Hipolito M. Borges, Rosana S.A. S. Furtado, Natalia Gomes Diogo, Islane M. C. Verçosa, Eduarda Tartarella-Nascimento

PMC · DOI: 10.5935/0004-2749.2022-0375 · Arquivos Brasileiros de Oftalmologia · 2024-09-16

## TL;DR

This study evaluates visual function and acuity in children with congenital Zika syndrome and finds that early visual intervention may improve outcomes.

## Contribution

The study provides new insights into visual acuity and cerebral vision impairment in children with congenital Zika syndrome.

## Key findings

- Grating visual acuity tests revealed low vision in all children with congenital Zika syndrome.
- Functional vision evaluation showed cerebral vision impairment in all patients.
- Visual acuity improved in six children following early visual intervention.

## Abstract

This study aimed to assess grating visual acuity and functional vision in
children with congenital Zika syndrome.

Initial and final grating visual acuity was measured using Teller acuity
cards. Cerebral vision impairment standardized tests were used to assess
functional vision. Patients were referred to the early visual intervention
program for visually disabled children. Neuroimaging was performed.

In this study, 10 children were included with an age range of 1-37 months.
Eight patients presented with macular atrophic scars. Neuroimaging revealed
microcephaly and cerebral abnormalities in all patients. Low vision and
cerebral vision impairment characteristics were observed in all children.
The final grating visual acuity in this group varied from 3.00 to 0.81
logMAR.

The grating visual acuity test revealed low vision in all children with
congenital Zika syndrome. Functional vision evaluation revealed cerebral
vision impairment characteristics in all patients, who were referred to the
early visual intervention program. Visual acuity improved in six
children.

## Linked entities

- **Diseases:** congenital Zika syndrome (MONDO:0000890)

## Full-text entities

- **Diseases:** congenital Zika syndrome (MESH:D000071243), microcephaly (MESH:D008831), cerebral abnormalities (MESH:D014402), Cerebral vision impairment (MESH:D014786), Low vision and cerebral vision impairment (MESH:D015354), atrophic scars (MESH:D002921)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12590407/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12590407/full.md

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Source: https://tomesphere.com/paper/PMC12590407