# Electrosurgical hysteroscopic metroplasty for septate uterus: a single-center retrospective analysis of safety, adhesion rates, and perioperative outcomes

**Authors:** Elvin Piriyev, Sven Schiermeier, Thomas Römer

PMC · DOI: 10.1007/s00404-025-08169-2 · Archives of Gynecology and Obstetrics · 2025-09-04

## TL;DR

This study evaluates the safety and outcomes of hysteroscopic surgery for correcting a septate uterus, finding it to be safe with low complication rates.

## Contribution

The study provides new insights into the safety and effectiveness of monopolar and bipolar electrosurgical metroplasty for septate uterus.

## Key findings

- No major complications like uterine perforation or fluid-overload occurred in 155 procedures.
- Intrauterine adhesions were observed in 4.3% of cases, with minimal infection rates.
- Bipolar systems were used in 65.1% of cases and associated with isotonic fluid use, enhancing safety.

## Abstract

To evaluate the safety, adhesion rates, and perioperative outcomes of monopolar and bipolar electrosurgical hysteroscopic metroplasty in women with a septate uterus.

We conducted a single‐center retrospective analysis of 155 consecutive patients who underwent same-session laparoscopy and hysteroscopic septum resection between January 2021 and January 2025. Procedures were performed under surgeon discretion using either a monopolar loop with glycine distension or a bipolar loop with isotonic Ringer’s lactate. Postoperative prophylaxis against intrauterine adhesions comprised hyaluronic acid gel—with or without a copper intrauterine device—and, in selected extensive resections, a three‐month estrogen–progestin regimen. Endometriosis was diagnosed laparoscopically and, when lesions were excised, confirmed histologically.

The most common indications for the surgery were endometriosis (40.6%), recurrent pregnancy loss (38.0%), and infertility (19.3%). Septal morphology was subseptate in 67.7%, septate in 20.0%, and complete septate in 12.2%, and bipolar energy was used in 65.1% of procedures. No uterine perforations, fluid-overload syndromes, or major hemorrhages occurred, and one case of postoperative endometritis (0.6%) was recorded. Second-look hysteroscopy, performed in 69 patients (44.5%), showed intrauterine adhesions in 3/69 (4.3%; grade I 2.9%, grade II 1.4%); residual septal tissue was observed in 50/69 (72.5%), predominantly in extensive septa. Histologically confirmed endometriosis, identified on concomitant laparoscopy, was present in 126/155 (81.3%) and did not differ across septal types (p = 0.103).

Monopolar and bipolar electrosurgical hysteroscopic metroplasty showed a good safety profile with negligible major complications, low adhesion rates, and minimal infection. Bipolar systems further enhance safety by enabling isotonic fluid use.

## Linked entities

- **Chemicals:** glycine (PubChem CID 750), Ringer’s lactate (PubChem CID 6335487)
- **Diseases:** endometriosis (MONDO:0005133)

## Full-text entities

- **Diseases:** infertility (MESH:D007246), Endometriosis (MESH:D004715), adhesions (MESH:D000267), endometritis (MESH:D004716), pregnancy loss (MESH:D000022), hemorrhages (MESH:D006470), infection (MESH:D007239), uterine perforations (MESH:D014595)
- **Chemicals:** glycine (MESH:D005998), lactate (MESH:D019344), hyaluronic acid (MESH:D006820)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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Source: https://tomesphere.com/paper/PMC12589382