# The impact of blood flow restriction combined with variable resistance training at different loads on lower limb strength and explosiveness in collegiate basketball players

**Authors:** Wuwen Peng, Zhanming Zhang, Di Lu, Zhentao Li, Guoxing Li, Jian Sun, Duanying Li

PMC · DOI: 10.3389/fphys.2025.1670071 · Frontiers in Physiology · 2025-10-23

## TL;DR

This study found that both low-load blood flow restriction training and high-load resistance training improved lower limb strength and explosiveness in college basketball players.

## Contribution

The study compares the effectiveness of blood flow restriction combined with variable resistance training at different loads in collegiate athletes.

## Key findings

- Both BFR-VRT and VRT groups showed significant improvements in lower-limb performance metrics.
- The control group showed no significant changes in performance.
- BFR-VRT showed comparable or slightly better results than VRT under lower external load.

## Abstract

This study compared the effects of an 8-week program of low-load blood flow restriction training combined with chain-based variable resistance training (BFR-VRT) and high-load chain-based variable resistance training (VRT) on lower-limb performance in male college basketball players. A total of 27 players were randomly assigned to the BFR-VRT group (n = 9), the variable resistance training group (n = 9), or a control group (n = 9). The BFR-VRT protocol used pneumatic cuffs applied to the proximal thighs, with training pressure set at 180 mmHg, and combined a 10% 1RM barbell load with 10%–30% 1RM from chains, whereas the VRT protocol consisted of a 55% 1RM barbell load plus 10%–30% 1RM from chains. The control group did not receive any resistance training. Repeated-measures Repeated-measures ANOVA showed significant within-group improvements in SQ-1RM, LTC, RTC, countermovement jump, squat jump, DJ-RSI, standing long jump, and 30-m in both the BFR-VRT and VRT groups (all p < 0.05), whereas the CON group showed no significant change (p > 0.05). Between-group comparisons indicated no significant differences among the three groups on these outcomes (all p > 0.05). In conclusion, both BFR-VRT and VRT improved lower-limb performance; under a lower external load, BFR-VRT showed effects comparable to, or trending greater than, VRT on certain performance measures.

https://www.chictr.org.cn/showprojEN.html?proj=201896, identifier ChiCTR2400086132.

## Full-text entities

- **Genes:** RPS6KB1 (ribosomal protein S6 kinase B1) [NCBI Gene 6198] {aka PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA}, NOS1 (nitric oxide synthase 1) [NCBI Gene 4842] {aka IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS}, GH1 (growth hormone 1) [NCBI Gene 2688] {aka GH, GH-N, GHB5, GHN, IGHD1A, IGHD1B}, HGF (hepatocyte growth factor) [NCBI Gene 3082] {aka DFNB39, F-TCF, HGFB, HPTA, SF}, MSTN (myostatin) [NCBI Gene 2660] {aka GDF8, MSLHP}
- **Diseases:** dizziness (MESH:D004244), numbness (MESH:D006987), ischemic (MESH:D002545), hypertrophy (MESH:D006984), contractile impairment (MESH:D060825), cardiovascular disease (MESH:D002318), muscle hypertrophy (MESH:C536106), skin irritation (MESH:D012871), lower limb injury (MESH:D038061), pain (MESH:D010146), loss of balance (MESH:D016388), injuries (MESH:D014947), hypoxia (MESH:D000860), BFRT (MESH:D002313), fatigue (MESH:D005221), tingling (MESH:D010292), ankle or arm injuries (MESH:D016512), hypoxic (MESH:D002534)
- **Chemicals:** ADP (MESH:D000244), lactate (MESH:D019344), inorganic phosphate (MESH:D010710), VRT (-), NO (MESH:D009569), hydrogen (MESH:D006859), testosterone (MESH:D013739), Iron (MESH:D007501)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12588841/full.md

## References

64 references — full list in the complete paper: https://tomesphere.com/paper/PMC12588841/full.md

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Source: https://tomesphere.com/paper/PMC12588841