# Impact of Combined Lentectomy, Vitrectomy, and Trabeculectomy on Secondary Glaucoma due to Lens Dislocation

**Authors:** Yuxin Zhao, Zhaoxia Wang, Jing Liu, Shanshan Yue

PMC · DOI: 10.1155/joph/6057819 · Journal of Ophthalmology · 2025-10-29

## TL;DR

This study shows that combining three eye surgeries effectively treats glaucoma caused by dislocated lenses, with high success rates in controlling eye pressure and improving vision.

## Contribution

The study demonstrates the combined surgical approach's efficacy for secondary glaucoma due to lens dislocation.

## Key findings

- 90% of patients achieved successful intraocular pressure control post-surgery.
- Visual acuity improved in 90% of cases after the combined procedure.
- Common complications included follicles, low eye pressure, and choroidal detachment.

## Abstract

This study aims to evaluate the clinical effectiveness of combining lentectomy, vitrectomy, and trabeculectomy in treating secondary glaucoma caused by lens dislocation.

We retrospectively analyzed data from 20 cases (20 eyes) of traumatic lens dislocation accompanied by secondary glaucoma. The patients underwent standard 3-port pars plana vitrectomy and the upper trabeculectomy. Mitomycin C (MMC) was applied below scleral flap during surgery. We evaluated preoperative and postoperative visual acuity, intraocular pressure (IOP), and any complications.

Postsurgery, visual acuity improved in 18 of the 20 eyes (90%). The operation was considered successful if postsurgery, the use of topical antiglaucoma drugs was no longer necessary or reduced, and the IOP was controlled within the range of 6–21 mmHg. Of the cases studied, 18 eyes (90%) had a successful outcome, while 2 eyes (10%) were unsuccessful, with an IOP of less than 6 mmHg. All 20 eyes (100%) developed follicles postoperatively. Complications included intraocular hemorrhage in 3 eyes, low intraocular pressure in 6 eyes, choroidal detachment in 4 eyes, and hyperfiltration in 2 eyes.

The combination of lentectomy, vitrectomy, and trabeculectomy presents a safe and effective method for reducing intraocular pressure and improving visual acuity in patients with secondary glaucoma resulting from lens dislocation.

## Linked entities

- **Chemicals:** Mitomycin C (PubChem CID 5746)

## Full-text entities

- **Diseases:** Glaucoma (MESH:D005901), intraocular hemorrhage (MESH:D064090), choroidal detachment (MESH:D000080324), Lens Dislocation (MESH:D007906)
- **Chemicals:** MMC (MESH:D016685)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12588741/full.md

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Source: https://tomesphere.com/paper/PMC12588741