# A Retrospective Study Analyzing Sexually Transmitted Infections and Bacterial Vaginosis

## TL;DR

This study finds that sexually transmitted infections and bacterial vaginosis are strongly linked, especially in women of childbearing age.

## Contribution

The study provides new demographic insights into the correlation between STIs and bacterial vaginosis.

## Key findings

- Women of childbearing age had a significantly higher prevalence of STI or BV compared to older age groups.
- There was a highly significant likelihood of having both STIs and BV compared to having only one infection.
- Ethnicity was not significantly associated with positive STI or BV results.

## Abstract

Background: Sexually transmitted infections (STIs) are often caused by bacteria, viruses, parasites, and fungi. Some STIs include herpes, human papillomavirus (HPV), Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis, whose risk increases significantly in the presence of bacterial vaginosis (BV), an infection that creates a bacterial imbalance in the body. Despite this relationship, there is limited understanding of this correlation across varying demographics, such as age and ethnicity.

Methods: In a retrospective cohort of 175 symptomatic specimens, using results from the Aptima Multitest Swab Specimen Collection Kit and the ThinPrep Pap Test to assess bacterial vaginosis, and the Aptima Urine Specimen Collection Kit and HealthLink TransPorter Sterile Transport Swab to assess STIs, this study evaluated the correlation between both infections.

Results: The median age was 22 years (range 18-62). BV was positive in 14.3% of African Americans, 61.1% of Hispanics, 3.4% of Pacific Islanders, and 21% of White participants. STI was positive in 44%, BV in 76.6%, and either STI or BV in 100% of cases. Individuals in the childbearing age group had a significantly higher prevalence of STI or BV (73.7%) compared to perimenopausal (17.1%) or menopausal (9.1%) age groups (chi-square 130.09; p<0.0001). There was no significant relationship between ethnicity and positive STI or BV (chi-square 19.8; p=0.7). The likelihood of having both STIs and BV was highly significant compared to having only one infection (chi-square 72.03; p<0.0001).

Conclusions: Our findings suggest that both STIs and BV are significantly associated with a higher likelihood of concomitant infection. Women of childbearing age have a higher susceptibility to developing both STIs and BV. This study underscores the need for prevention strategies and early screening in high-risk demographics to improve patients’ reproductive health.