# Does oxygen limitation set thermal limits in aquatic ectotherms?

**Authors:** Diana Madeira

PMC · DOI: 10.1371/journal.pbio.3003441 · PLOS Biology · 2025-11-05

## TL;DR

A new study questions the idea that oxygen shortage limits how well aquatic animals can handle heat, sparking new debate.

## Contribution

The study shows that oxygen supersaturation has little protective effect on aquatic ectotherms under heat stress.

## Key findings

- Oxygen limitation may not be the main factor in thermal tolerance of aquatic ectotherms.
- Supersaturated oxygen levels provided minimal protection during heat stress.
- The findings challenge the prevailing oxygen limitation hypothesis.

## Abstract

Thermal tolerance determines winners and losers in a warming world. Oxygen limitation has been the primary hypothesis for the mechanistic basis of thermal tolerance. A new study in PLOS Biology suggests otherwise, reigniting debate on what truly sets thermal limits.

Oxygen limitation is thought to represent a key mechanism underlying thermal tolerance. This primer discusses how a recent PLOS Biology article challenges this idea, by showing minimal protective effects of oxygen supersaturation in aquatic ectotherms exposed to heat stress.

## Full-text entities

- **Chemicals:** Oxygen (MESH:D010100)

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12588527/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12588527/full.md

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Source: https://tomesphere.com/paper/PMC12588527