This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
Retraction: Genistein Improves 3-NPA-Induced Memory Impairment in Ovariectomized Rats: Impact of Its Antioxidant, Anti-Inflammatory and Acetylcholinesterase Modulatory Properties
Abstract
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TopicsPhytoestrogen effects and research · Menopause: Health Impacts and Treatments · Stress Responses and Cortisol
Following the publication of this article [1], concerns were raised for Figs 3, 6, 7, 8 and 9. Specifically, there are regions within the following figure panels which appear similar:
In light of the above concerns that question the reliability and integrity of these results, the PLOS One Editors retract this article. In addition, results presented in Fig 3 of this article [1] appear similar to results presented in Fig 5 of [2, retracted in 3], published later by the same researchers. All authors either did not respond directly or could not be reached.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Menze ET, Esmat A, Tadros MG, Abdel-Naim AB, Khalifa AE (2015) RETRACTED: Genistein Improves 3-NPA-Induced Memory Impairment in Ovariectomized Rats: Impact of Its Antioxidant, Anti-Inflammatory and Acetylcholinesterase Modulatory Properties. P Lo S ONE 10(2): e 0117223. doi: 10.1371/journal.pone.0117223 PMC 432641625675218 · doi ↗ · pubmed ↗
- 2Menze ET, Esmat A, Tadros MG, Khalifa AE, Abdel-Naim AB. (2016) Genistein improves sensorimotor gating: Mechanisms related to its neuroprotective effects on the striatum. Neuropharmacology, 105:35–46. doi: 10.1016/j.neuropharm.2016.01.00726764242 · doi ↗ · pubmed ↗
- 3Menze ET, Esmat A, Tadros MG, Khalifa AE, Abdel-Naim AB. (2024) Retraction Notice to “Genistein improves sensorimotor gating: Mechanisms related to its neuroprotective effects on the striatum” [Neuropharm. 105 (2016) 35–46]. Retraction in: Neuropharmacology, 2024 Jul 1;252:109964. doi: 10.1016/j.neuropharm.2024.10996438644148 · doi ↗ · pubmed ↗