# Rare but relevant: Cannabis use and myocardial infarction

**Authors:** Prianka Padmanathan, Emmert Roberts

PMC · DOI: 10.1111/add.70128 · Addiction (Abingdon, England) · 2025-07-01

## TL;DR

This paper discusses how cannabis use may be linked to heart attacks, especially in young, healthy individuals, and highlights the need for better research and clinical awareness.

## Contribution

The paper emphasizes the need for detailed studies on cannabis use patterns and their cardiovascular risks, which are currently underexplored.

## Key findings

- Cannabis use may increase the risk of myocardial infarction in young, healthy individuals.
- Current studies lack detailed data on cannabis consumption patterns and their cardiovascular effects.
- Accurate documentation of cannabis use is essential for future research and clinical care.

## Abstract

Pre‐clinical research and case reports have linked cannabis use to myocardial infarction (MI) since the 1970s. The association with MI may be specific to certain types and patterns of cannabis use as well as certain consumer characteristics; however, due to limited data availability, meta‐analyses examining the association between cannabis use and MI typically report only broad binary categorisations of use vs. no use. Robust prospective studies that capture the complexities of consumption patterns are required to inform causal inferences. In the meantime, clinicians should be aware of the potential increased risk of myocardial infarction in young healthy patients presenting with chest pain and a recent history of cannabis use. Accurate assessment and documentation of recent cannabis use is also essential to improve future research and identify and monitor interactions with cardiovascular medications.

## Linked entities

- **Diseases:** myocardial infarction (MONDO:0005068)

## Full-text entities

- **Diseases:** MI (MESH:D009203), chest pain (MESH:D002637)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

45 references — full list in the complete paper: https://tomesphere.com/paper/PMC12586771/full.md

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Source: https://tomesphere.com/paper/PMC12586771