# Effect of XP-endo Finisher and EDDY activation on post-operative pain after single-visit endodontic treatment: a randomized controlled clinical trial

## TL;DR

This study compares new dental irrigation techniques to traditional methods and finds they may reduce post-treatment pain in root canal procedures.

## Contribution

The study evaluates the impact of XP-endo Finisher and EDDY activation on post-operative pain in single-visit endodontic treatment.

## Key findings

- Pain scores significantly decreased over time in all groups.
- Group II (XP-endo Finisher) showed the lowest pain levels, followed by Group III (EDDY activation), with Group I (conventional irrigation) reporting the highest.
- Female participants had significantly higher odds of reporting pain.

## Abstract

Advanced irrigation techniques, such as the XP-endo Finisher file and sonic EDDY system, have been introduced to overcome the limitations of conventional needle irrigation by enhancing irrigant penetration and disinfection. However, their influence on post-operative pain remains under investigation. This study aimed to evaluate the effect of these techniques on post-operative pain following single-visit root canal treatment. Thirty patients requiring endodontic treatment for asymptomatic vital maxillary central incisors or canines were enrolled. All procedures were performed in a single visit using the ProTaper Universal rotary system. Irrigation was carried out with 2.5% sodium hypochlorite (NaOCl). Participants were randomly assigned into three equal groups based on the final irrigation protocol: Group I – conventional needle irrigation (control), Group II – XP-endo Finisher file, and Group III – sonic EDDY activation. Post-operative pain was assessed using a Visual Analogue Scale (VAS) at 8, 24, and 48 h, and at 1 and 2 weeks. Data were statistically analyzed with significance set at P ≤ 0.05. Pain scores significantly decreased overtime in all groups. While between-group differences were not statistically significant, within-group reductions were significant. Group II exhibited the lowest pain levels, followed by Group III, while Group I reported the highest. Additionally, female participants had significantly higher odds of reporting pain. The XP-endo Finisher and sonic EDDY systems resulted in better pain reduction over time than conventional needle irrigation, with XP-endo Finisher being most effective.

Clinical relevance: Advanced irrigation systems may enhance patient comfort and compliance by reducing post-operative pain after endodontic therapy.

Clinical trial registration: The study protocol was registered on https://beta.clinicaltrials.gov identifier: NCT05450003 on (08/07/2022).