# Autologous Platelet‐Rich Plasma and Shockwave Therapy for Refractory Middle Femoral Nonunion: A Case Report

**Authors:** Chao Cheng, Ri‐chao Pang, Hua‐ge Wang, Zhong‐lin Xiao, Zheng‐dong Wang, Jin‐qi Zheng, Wenchun Wang

PMC · DOI: 10.1002/ccr3.71400 · Clinical Case Reports · 2025-11-04

## TL;DR

A patient with a long-lasting femoral nonunion healed after a combination of PRP therapy, shockwave treatment, and rehabilitation.

## Contribution

The paper presents a novel combined treatment approach for refractory bone nonunion using PRP and shockwave therapy.

## Key findings

- The patient achieved clinical fracture healing after multiple failed surgeries.
- Combining PRP therapy with shockwave intervention and rehabilitation was effective.
- The treatment approach offers practical insights for managing complex bone nonunions.

## Abstract

This case report details a patient with persistent middle femoral nonunion unresponsive to multiple surgeries. PRP therapy, shockwave intervention, and structured rehabilitation were combined to achieve clinical fracture healing. This multifaceted treatment approach illustrates the coordinated use of PRP and physical modalities, offering practical insight for the clinical treatment of complex bone nonunion.

## Full-text entities

- **Diseases:** fracture (MESH:D050723), bone nonunion (MESH:D001847), Nonunion (MESH:C538144)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12586344/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12586344/full.md

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Source: https://tomesphere.com/paper/PMC12586344