# Coronary Fistula–Induced Ventricular Tachycardia From Thrombotic Cyst Compression: A Case Report

**Authors:** Xuelin Lu, Xiaoqin Duan, Zuoan Qin

PMC · DOI: 10.1111/anec.70121 · Annals of Noninvasive Electrocardiology · 2025-11-04

## TL;DR

A rare case of ventricular tachycardia caused by a thrombotic cyst from a coronary artery fistula is reported, highlighting its life-threatening complications.

## Contribution

This case report highlights the rare but severe complication of thrombotic cysts from coronary artery fistulas leading to ventricular tachycardia.

## Key findings

- Thrombotic cysts from coronary artery fistulas can cause irreversible myocardial fibrosis and ventricular tachycardia.
- ECG findings like fragmented QRS and ST depression indicate irreversible myocardial damage in such cases.
- Surgical resection may not prevent recurrence of VT, leading to cardiogenic shock and death.

## Abstract

Coronary artery fistula (CAF) complicated by thrombotic cyst formation is a rare cause of ventricular tachycardia (VT), involving ischemia and mechanical compression.

A 55‐year‐old woman presented with palpitations, chest pain, monomorphic VT (negative V1–V6), and elevated troponin I. Imaging revealed a large right ventricular cyst. Surgical resection confirmed a thrombotic cyst communicating with a CAF. Postoperative VT recurred, leading to cardiogenic shock and death.

CAF‐related thrombotic cysts can cause irreversible myocardial fibrosis, creating a persistent VT substrate unresponsive to anatomical intervention alone. ECG markers (fragmented QRS, ST depression) reflect irreversible damage.

At presentation. Initial electrocardiogram: the presence of exclusively negative QRS complexes across all precordial leads (V1 through V6) supported the diagnosis of ventricular tachycardia.

## Linked entities

- **Diseases:** ventricular tachycardia (MONDO:0005477), cardiogenic shock (MONDO:0800175)

## Full-text entities

- **Diseases:** cardiogenic shock (MESH:D012770), ischemia (MESH:D007511), Thrombotic Cyst (MESH:D003560), palpitations (MESH:D006331), monomorphic (MESH:D000236), Coronary Fistula (MESH:D005402), depression (MESH:D003866), VT (MESH:D017180), myocardial fibrosis (MESH:D005355), chest pain (MESH:D002637), CAF (MESH:D003324), death (MESH:D003643)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12586343/full.md

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Source: https://tomesphere.com/paper/PMC12586343