# Mediating Role of Internet Use in Cognitive-Depressive Pathways: A Random Intercept Cross-Lagged Panel Modeling Approach

**Authors:** Zhichao Wang, Zhongliang Zhou, Jiao Lu, Xinyue Zhang, Xiaohui Zhai, Yan Zhuang

PMC · DOI: 10.3389/ijph.2025.1608478 · International Journal of Public Health · 2025-10-21

## TL;DR

This study shows that internet use partially explains the link between depression and cognitive decline in middle-aged and older adults.

## Contribution

The study introduces internet use as a mediator in the bidirectional relationship between depression and cognition.

## Key findings

- Cognitive decline predicts increased depressive symptoms, and vice versa.
- Internet use partially mediates this relationship, explaining about 8-9% of the total effect.
- The mediating effect of internet use is stronger in middle-aged adults than in older adults.

## Abstract

Prior work has identified an inverse relationship between depression and cognition in older adults, but the mechanisms underlying this association remain unclear. This study investigated whether internet use mediates this relationship in middle-aged and older adults.

Data were drawn from the China Health and Retirement Longitudinal Study (CHARLS) from 2015 to 2020 (n = 9,610). The Random Intercept Cross-Lagged Panel Model (RI-CLPM) with mediation analysis was used; subgroup analyses were conducted for middle-aged (45–64) and older (65+) adults.

At the between-person level, a significant negative correlation was found between cognitive function and depressive symptoms. Within-person analysis revealed a bidirectional relationship: poorer cognitive function predicted increased depressive symptoms (β* = −0.080, p < 0.001), and conversely, increased depressive symptoms predicted poorer cognitive function (β* = −0.019, p < 0.05). Internet use partially mediated this relationship, accounting for 8.58% and 9.69% of the total effects, respectively. This mediating effect was stronger in middle-aged adults than in older adults.

These results emphasize the continued importance of exploring multidisciplinary interventions to mitigate depressive symptoms and delay cognitive decline in middle-aged and older adult populations.

## Linked entities

- **Diseases:** depression (MONDO:0002050)

## Full-text entities

- **Diseases:** depression (MESH:D003866), Cognitive-Depressive (MESH:D060825), cognitive decline (MESH:D003072)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12583110/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12583110/full.md

## References

52 references — full list in the complete paper: https://tomesphere.com/paper/PMC12583110/full.md

---
Source: https://tomesphere.com/paper/PMC12583110