# The detoxification paradox: Rethinking microbial dehalogenation in environmental remediation

**Authors:** Qian Wang, Shuai Wang, Yueli Hu, Jiaxin Wu, Shanyuan Niu

PMC · DOI: 10.1016/j.eehl.2025.100190 · 2025-10-03

## Full-text entities

- **Genes:** PFAS (phosphoribosylformylglycinamidine synthase) [NCBI Gene 5198] {aka FGAMS, FGAR-AT, FGARAT, GATD8, PURL}, TCEA1 (transcription elongation factor A1) [NCBI Gene 6917] {aka GTF2S, SII, TCEA, TF2S, TFIIS}, AHR (aryl hydrocarbon receptor) [NCBI Gene 196] {aka FVH3, RP85, bHLHe76}
- **Diseases:** carcinogenic (MESH:D011230), reproductive failure (MESH:D051437), toxicity (MESH:D064420)
- **Chemicals:** water (MESH:D014867), chloroform (MESH:D002725), 1,1,1-trichloroethane (MESH:C024566), iron (MESH:D007501), halogen (MESH:D006219), VC (MESH:D014752), HOPs (-), TCE (MESH:D014241), PBDEs (MESH:D055768), acetophenones (MESH:D000098), PCB (MESH:D011078), ethene (MESH:C036216), PCE (MESH:D013750)
- **Species:** Dehalococcoides (genus) [taxon 61434], Streptococcus (genus) [taxon 1301], Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12581702/full.md

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Source: https://tomesphere.com/paper/PMC12581702