# Hemopericardium Following Norovirus Gastroenteritis in a Child: An Uncommon Presentation

**Authors:** Maha Hamed, Venkatachalam Karuppaswamy

PMC · DOI: 10.7759/cureus.93767 · Cureus · 2025-10-03

## TL;DR

A child developed a rare heart complication called hemopericardium after a norovirus stomach infection, highlighting the need for early detection and treatment.

## Contribution

This is the first reported case of hemopericardium in a child linked to norovirus infection.

## Key findings

- A 20-month-old child developed hemopericardium following norovirus gastroenteritis.
- Pericardiocentesis successfully treated the condition, with full recovery observed.
- The case suggests clinicians should consider cardiac complications in children with post-viral symptoms.

## Abstract

Norovirus is a leading cause of acute gastroenteritis in children and is typically a self-limiting illness. Cardiac complications are exceptionally rare. To our knowledge, this is the first reported case of hemopericardium associated with norovirus infection in a child.

We describe a 20-month-old previously healthy boy who presented with respiratory distress and fatigue two weeks after an episode of acute norovirus gastroenteritis. Investigations revealed severe anemia, elevated D-dimer, and a large hemorrhagic pericardial effusion with echocardiographic evidence of tamponade. Extensive workup excluded trauma, coagulopathy, autoimmune disease, and other infectious causes. The patient underwent urgent pericardiocentesis, draining 200 mL of hemorrhagic fluid. He improved rapidly and remained asymptomatic, with serial echocardiograms showing complete resolution of the effusion up to six weeks post-discharge.

Hemopericardium is a rare but life-threatening complication of pediatric norovirus infection. Clinicians should consider cardiac involvement in children with unexplained cardiopulmonary findings following viral gastroenteritis. Early echocardiography and prompt intervention are essential for favorable outcomes.

## Linked entities

- **Diseases:** hemopericardium (MONDO:0005783)

## Full-text entities

- **Diseases:** anemia (MESH:D000740), Hemopericardium (MESH:D010490), autoimmune disease (MESH:D001327), gastroenteritis (MESH:D005759), respiratory distress (MESH:D012128), trauma (MESH:D014947), coagulopathy (MESH:D001778), viral gastroenteritis (MESH:D014777), fatigue (MESH:D005221), Norovirus Gastroenteritis (MESH:D017250), effusion (MESH:D000080324), hemorrhagic (MESH:D006470), tamponade (MESH:D002305), Cardiac complications (MESH:D006331)
- **Species:** Homo sapiens (human, species) [taxon 9606], Norovirus (genus) [taxon 142786]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12580614/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12580614/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12580614/full.md

---
Source: https://tomesphere.com/paper/PMC12580614