# Editorial: Deciphering microbial metabolites: their impact on gastrointestinal and metabolic health

**Authors:** William J. Massey, Shafiya Imtiaz Rafiqi

PMC · DOI: 10.3389/fnut.2025.1716777 · Frontiers in Nutrition · 2025-10-20

## Full-text entities

- **Genes:** Gpbar1 (G protein-coupled bile acid receptor 1) [NCBI Gene 227289] {aka BG37, GPCR, GPR131, M-BAR, TGR5}, Gcg (glucagon) [NCBI Gene 14526] {aka GLP-1, Glu, PPG}, Ffar3 (free fatty acid receptor 3) [NCBI Gene 233080] {aka Gm478, Gpr41}, Ffar2 (free fatty acid receptor 2) [NCBI Gene 233079] {aka GPCR43, Gpr43}
- **Diseases:** diarrhea (MESH:D003967), obesity (MESH:D009765), MASH (MESH:D005234), T2DM (MESH:D003924), Atopic Dermatitis (MESH:D003876), metabolic diseases (MESH:D008659), hyperuricemia (MESH:D033461), glucose intolerance (MESH:D018149), female infertility (MESH:D007247), CRC (MESH:D015179), GLM (MESH:D058890), breast (MESH:D061325), cirrhosis (MESH:D005355), MASLD (MESH:D008107), inflammation (MESH:D007249), hepatitis B (MESH:D006509), food allergy (MESH:D005512), insulin resistance (MESH:D007333), GI and metabolic diseases (MESH:D005767), gallstone (MESH:D042882), tumor (MESH:D009369)
- **Chemicals:** senna leaf (MESH:D012676), lipid (MESH:D008055), metformin (MESH:D008687), butanoic acid (MESH:D020148), tauroursodeoxycholic acid (MESH:C031655), BAs (MESH:D001464), SCFA (MESH:D005232), fucose (MESH:D005643), isohexanoic acid (MESH:C034527), isovaleric acid (MESH:C008216), cholesterol (MESH:D002784), adenine (MESH:D000225), acetate (MESH:D000085), 21-hydroxy-pregnenolone (MESH:C052374), TMAO (MESH:C005855), bile acids (MESH:D001647), F. sennae (-), fat (MESH:D005223), tocopherols (MESH:D024505), N-acetyl-D-glucosamine (MESH:D000117), propionate (MESH:D011422), uric acid (MESH:D014527), amino acid (MESH:D000596), homoserine (MESH:D006714), butyrate (MESH:D002087)
- **Species:** gut metagenome (species) [taxon 749906], Lactobacillus acidophilus (species) [taxon 1579], Danio rerio (leopard danio, species) [taxon 7955], Acidipropionibacterium acidipropionici (species) [taxon 1748], Homo sapiens (human, species) [taxon 9606], Bacteroides (genus) [taxon 816], Mus musculus (house mouse, species) [taxon 10090]

## Full text

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## References

4 references — full list in the complete paper: https://tomesphere.com/paper/PMC12580592/full.md

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Source: https://tomesphere.com/paper/PMC12580592