# Research Progress on Local Treatment of Malignant Pleural Effusion

**Authors:** Yanjun DU, Ping ZHAN, Tangfeng LV, Yong SONG

PMC · DOI: 10.3779/j.issn.1009-3419.2025.102.32 · Chinese Journal of Lung Cancer · 2025-08-20

## TL;DR

This paper reviews recent local treatment approaches for malignant pleural effusion caused by primary tumors, focusing on new drugs and methods.

## Contribution

The paper provides an updated overview of novel local treatment strategies for malignant pleural effusion.

## Key findings

- Recent studies have explored new drugs for local treatment of malignant pleural effusion.
- Various innovative methods have been developed to address effusion caused by primary tumors.
- The paper summarizes the current state of local treatment research in this area.

## Abstract

恶性胸腔积液（malignant pleural effusion, MPE）是指由原发于胸膜或其他部位的恶性肿瘤转移所引起的胸膜腔积液，患者预后差。目前MPE的治疗主要有针对MPE的全身抗肿瘤治疗以及针对原发性肿瘤引起MPE的局部治疗。有关MPE局部治疗的文献报道颇多，方法涉及面广。本文综述近年来针对原发性肿瘤引起的MPE的局部治疗研究进展，总结近年来出现的新药物及新手段。

## Full-text entities

- **Diseases:** tumor (MESH:D009369), MPE (MESH:D016066)

## Full text

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## References

53 references — full list in the complete paper: https://tomesphere.com/paper/PMC12580388/full.md

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Source: https://tomesphere.com/paper/PMC12580388