# Unexpected late-onset bleeding following thyroid surgery: case report and review of the literature

**Authors:** Marco Marcianò, Bianca Vicari, Giuseppina Orlando, Giuseppina Melfa, Isabella Campo, Giuseppe Salamone, Gregorio Scerrino

PMC · DOI: 10.3389/fsurg.2025.1682888 · Frontiers in Surgery · 2025-10-20

## TL;DR

A rare case of late-onset bleeding after thyroid surgery is reported, occurring on the eighth day post-surgery in a patient on antiplatelet therapy.

## Contribution

Highlights a rare complication of postoperative bleeding occurring on the eighth day in a patient resuming antiplatelet therapy.

## Key findings

- Late-onset bleeding occurred on the eighth postoperative day in a patient on antiplatelet therapy.
- Hematoma was found in the right thyroid bed and subhyoid region with active bleeding from the superior thyroid vascular pedicle.
- Emphasizes the need for close monitoring and caution in patients requiring antiplatelet therapy post-surgery.

## Abstract

Postoperative hematoma is an uncommon but potentially life-threatening and unpredictable complication of thyroid surgery. We report a case of very late postoperative bleeding occurring on the eighth postoperative day (POD) in a patient undergoing right lobe thyroidectomy who had restarted antiplatelet therapy since the first POD. The patient was readmitted to the emergency department with complaints of progressive anterior neck swelling and bleeding from the wound but without respiratory distress. Under general anesthesia, cervical reexploration allowed the detection of a hematoma situated in the right thyroid bed and subhyoid region and active bleeding of the superior thyroid vascular pedicle. Although most bleeding occurs within 24 h, caution should be taken in patients who are in need of antiplatelet therapy, and close monitoring should also be advised at home after discharge.

## Full-text entities

- **Diseases:** respiratory distress (MESH:D012128), hematoma (MESH:D006406), bleeding (MESH:D006470), neck swelling (MESH:D006258)
- **Chemicals:** antiplatelet (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

36 references — full list in the complete paper: https://tomesphere.com/paper/PMC12580173/full.md

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Source: https://tomesphere.com/paper/PMC12580173