# Partial Splenic Embolization for Portal Hypertension Before Radical Nephrectomy in Renal Cell Carcinoma Patient: A Case Report

**Authors:** Shunsuke Watanabe, Keita Tamura, Kyohei Watanabe, Yuto Matsushita, Hiromitsu Watanabe, Daisuke Motoyama, Teruo Inamoto

PMC · DOI: 10.1002/iju5.70108 · IJU Case Reports · 2025-10-13

## TL;DR

Partial splenic embolization can help reduce surgical risks in patients with kidney cancer and liver issues before surgery.

## Contribution

The paper presents a case where partial splenic embolization improved surgical safety in a patient with renal cell carcinoma and portal hypertension.

## Key findings

- Partial splenic embolization increased platelet count and reduced collateral circulation.
- The procedure enabled a safe radical nephrectomy in a high-risk patient.
- It may expand treatment options for patients with coexisting portal hypertension and renal tumors.

## Abstract

Partial splenic embolization is a valuable option to manage hypersplenism and reduce portal pressure while preserving splenic function. It may improve surgical safety in patients with portal hypertension.

A 67‐year‐old Japanese male with renal cell carcinoma and hepatitis B‐related liver cirrhosis presented with thrombocytopenia, collateral vessels, and a splenorenal shunt. Due to concerns regarding surgical risk, partial splenic embolization was performed preoperatively. Following the procedure, the platelet count increased, and collateral circulation decreased. These improvements enabled a safe left radical nephrectomy.

Partial splenic embolization can be an effective preoperative strategy in patients with renal tumors and coexisting portal hypertension. By improving hematologic parameters and reducing vascular risk, it may facilitate curative surgery in high‐risk patients and expand treatment options.

## Linked entities

- **Diseases:** renal cell carcinoma (MONDO:0005086), hepatitis B (MONDO:0005344), portal hypertension (MONDO:0005080), thrombocytopenia (MONDO:0002049)

## Full-text entities

- **Diseases:** thrombocytopenia (MESH:D013921), hepatitis B (MESH:D006509), hypersplenism (MESH:D006971), liver cirrhosis (MESH:D008103), renal tumors (MESH:D007680), Renal Cell Carcinoma (MESH:D002292), Portal Hypertension (MESH:D006975), Splenic Embolization (MESH:D004617)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12580009/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12580009/full.md

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Source: https://tomesphere.com/paper/PMC12580009