# A Creative Solution for a Difficult Case: Endoluminal Negative Pressure Therapy for the Management of Colorectal Anastomotic Leak

**Authors:** Maziar Fazel Darbandi, Jessica Shanahan, David Hochman, Farhana Shariff

PMC · DOI: 10.7759/cureus.93785 · Cureus · 2025-10-03

## TL;DR

This paper presents a novel use of endoluminal negative pressure therapy to successfully manage a colorectal anastomotic leak when conventional methods failed.

## Contribution

The paper introduces a homemade endoluminal negative pressure therapy device for managing colorectal anastomotic leaks in a clinical setting.

## Key findings

- Endoluminal negative pressure therapy successfully controlled pelvic sepsis in a patient with a colorectal anastomotic leak.
- The homemade device led to a significant reduction in abscess size and allowed the patient to be safely discharged.
- This case suggests endoluminal negative pressure therapy is a feasible alternative for managing difficult colorectal leaks.

## Abstract

Rectal anastomotic leaks can lead to significant morbidity with potentially devastating consequences for patients’ intestinal continuity and quality of life, which are challenging to manage. With a growing interest in endoluminal negative pressure therapy (eNPT), which was first described for use in esophageal anastomotic leaks, the technique has been more recently adapted to colorectal anastomoses.

We discuss a case of a patient with rectal cancer, who underwent total neoadjuvant therapy, ultralow anterior resection, and diverting loop ileostomy. The patient suffered an anastomotic leak and presacral abscess. Attempts at conventional management to control pelvic sepsis were unsuccessful. We present the novel creation of an eNPT device (a manufactured one is not readily available in Canada), which allowed control of sepsis, substantial reduction in abscess size, and safe discharge home for the patient. This experience suggests this is a safe and feasible treatment alternative for this challenging problem.

## Linked entities

- **Diseases:** rectal cancer (MONDO:0006519)

## Full-text entities

- **Diseases:** rectal cancer (MESH:D012004), abscess (MESH:D000038), Anastomotic Leak (MESH:D057868), pelvic sepsis (MESH:D018805)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12579906/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12579906/full.md

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Source: https://tomesphere.com/paper/PMC12579906