# Thrombolysis With Tenecteplase in Cardiac Arrest Due to Massive Pulmonary Embolism

## TL;DR

A patient with a massive pulmonary embolism and cardiac arrest was successfully treated with tenecteplase and CPR.

## Contribution

This case highlights the successful use of tenecteplase in a prolonged CPR scenario for massive pulmonary embolism.

## Key findings

- Tenecteplase administration during CPR successfully resuscitated a patient with massive PE.
- The patient was extubated and discharged after supportive care including CRRT.

## Abstract

Pulmonary embolism (PE) is a life-threatening condition that can cause sudden hemodynamic collapse. Prompt diagnosis and timely thrombolysis can be life-saving, even in situations where prolonged cardiopulmonary resuscitation (CPR) is necessary. We present a case of a morbidly obese patient who had a cardiac arrest due to massive PE. Immediate initiation of CPR and administration of tenecteplase resulted in the successful resuscitation of the patient after 45 minutes of CPR. With the help of supportive management and continuous renal replacement therapy (CRRT), the patient was successfully extubated on the third day and discharged home in a stable condition.