# Optimizing Biomedical Health Efficiency: Unlocking the Full Potential of Life Science Innovation Through System Design

## TL;DR

The paper argues that healthcare systems need better design to fully benefit from biomedical innovations.

## Contribution

The authors propose an open-access dynamic design engine to align biomedical and health system innovation.

## Key findings

- Current healthcare systems struggle to adopt biomedical innovations due to system barriers.
- A collaborative design engine could improve the implementation of patient-centered innovations.
- Impact measurement is critical for ensuring sustainable and efficient health system changes.

## Abstract

Major advances in biomedical science have transformed healthcare. However, system barriers to the appropriate, timely, and equitable use of biomedical innovations have led to slow and inconsistent adoption, limiting and delaying our ability to leverage their full potential to improve health. System barriers include inconsistent coverage, imperfect information systems for decision making and real word evidence, policy constraints, system capacity, social influences on health, and infrastructure gaps.

We propose the development of an open access dynamic design “engine” to align biomedical and health system innovation. This engine will include coordinated collaborative design processes, frameworks, and tools, developed with input from all stakeholders, and centered around two critical, interdependent capabilities: (1) system design and (2) impact measurement. These capabilities will build capacity for efficient, model-driven design and implementation planning of sustainable, patient centered system innovations.

The stakes are high for both the clinical promise of transformational products and their budget impact. Our current healthcare system is not ready to maximize benefit from transformational science and emerging biomedical innovations. We need to help the healthcare system catch up with the science.