# A Unique Case of Compressive Optic Neuropathy From an Internal Carotid Artery Aneurysm

**Authors:** Daniel S. Boyes, Kiren Bashir, Jonathan M. Skarie, Ryan E. Chenevey

PMC · DOI: 10.1155/crop/6458555 · Case Reports in Ophthalmological Medicine · 2025-10-25

## TL;DR

A rare case of optic nerve damage caused by a large artery aneurysm highlights the importance of visual field testing in diagnosing central vs. peripheral vision loss.

## Contribution

Demonstrates that RAPD may be absent in bilateral compressive optic neuropathy, emphasizing the need for visual field testing.

## Key findings

- Bilateral compressive optic neuropathy can occur without a relative afferent pupillary defect.
- Visual field testing revealed a junctional scotoma pattern, indicating a central lesion.
- MRI confirmed a large right supraclinoid internal carotid artery aneurysm as the cause.

## Abstract

Compressive optic neuropathy (CON) is a condition characterized by optic nerve damage caused by abnormal mechanical pressure. Here, we report a rare case of bilateral CON due to a large, right supraclinoid internal carotid artery (ICA) aneurysm. A 66-year-old female presented to the clinic with complaints of prior, intermittent headaches and decreased visual acuity. Notably, no relative afferent pupillary defect (RAPD) was present on exam. Visual field testing revealed an inferior altitudinal defect oculus dexter (OD) and a superotemporal defect oculus sinister (OS). This visual field pattern strongly suggested a central lesion in the form of a junctional scotoma despite the noted absence of a RAPD on exam. Subsequent magnetic resonance imaging (MRI) revealed a large, right supraclinoid aneurysm, and the patient was treated accordingly. Through this case, one can appreciate how the classically described RAPD may not be present in all cases of CON if both optic nerves are affected. A provider must subsequently use other findings to distinguish between a central and peripheral nerve etiology. The importance of formal visual field testing in all cases of vision loss is highlighted to assess its etiology and aid in making this distinction between a central and peripheral lesion.

## Full-text entities

- **Diseases:** headaches (MESH:D006261), optic nerve damage (MESH:D020221), defect oculus sinister (MESH:D000013), scotoma (MESH:D012607), RAPD (MESH:D011681), supraclinoid internal carotid artery (ICA) aneurysm (MESH:D002340), inferior altitudinal defect oculus dexter (MESH:D056989), CON (MESH:D009408), vision loss (MESH:D014786), supraclinoid aneurysm (MESH:D000783)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12579560/full.md

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Source: https://tomesphere.com/paper/PMC12579560