# Traumatic Brain Injury in Pregnancy: A Single Level I Trauma Center Experience

**Authors:** Hector Fuentes Plata, Nisha K Dabhi, Shankar P Gopinath, Spyridoula Tsetsou

PMC · DOI: 10.7759/cureus.93709 · Cureus · 2025-10-02

## TL;DR

This study examines the rare but complex cases of traumatic brain injury in pregnant patients, highlighting diagnostic and treatment challenges.

## Contribution

The paper provides insights from a single Level I trauma center's experience with TBI during pregnancy, emphasizing the need for pooled data and updated guidelines.

## Key findings

- Only four pregnant patients with TBI were identified among 2,027 TBI admissions over 10 years.
- Two patients delivered viable infants via cesarean section, and outcomes ranged from home discharge to brain death.
- The study underscores the rarity and complexity of managing TBI in pregnant patients.

## Abstract

Traumatic brain injury (TBI) is less common in pregnancy than in the general population; however, it poses significant challenges in diagnosis and management. These include the potential teratogenicity of medications, radiation exposure from imaging modalities, physiological changes associated with pregnancy, and obstetric complications that may arise. Although there are general guidelines for trauma in the obstetric patient, they are not specific to TBI, and most recommendations are based on low-level evidence or institutional experiences.

We conducted a retrospective review of the hospital trauma registry over a 10-year period. We included all the patients admitted to our neurosurgical intensive care unit for TBI and confirmed pregnancy. The data was obtained through a chart review.

Among 2,027 TBI admissions, four patients were pregnant. Of these four patients, two underwent external ventricular drain placement; one required a decompressive craniectomy. Two patients delivered viable infants via cesarean section. Two patients were discharged home, and one to a personal care home. One patient was pronounced brain dead.

Our data confirmed the rarity of pregnancy in TBI. Even though this represents an infrequent clinical scenario, the complications and treatment can be challenging for clinicians. Therefore, pooled data from other level I trauma centers should be studied to formulate appropriate therapeutic directions, and the inclusion of this population in medical societies’ guidelines is necessary.

## Linked entities

- **Diseases:** traumatic brain injury (MONDO:0858950)

## Full-text entities

- **Diseases:** TBI (MESH:D000070642), brain dead (MESH:D001926), Trauma (MESH:D014947)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12579467/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12579467/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12579467/full.md

---
Source: https://tomesphere.com/paper/PMC12579467