# Predictors of acute hospital mortality from a 23-year database of emergency medical admissions

**Authors:** Richard Conway, Declan Byrne, Deirdre O’Riordan, Bernard Silke

PMC · DOI: 10.1007/s11845-025-04022-2 · Irish Journal of Medical Science · 2025-07-29

## TL;DR

This study analyzed 23 years of emergency medical admissions to identify factors affecting hospital mortality and found significant improvements over time.

## Contribution

The study provides long-term comparative data on emergency medical admission outcomes and identifies key predictors of mortality.

## Key findings

- 30-day in-hospital mortality decreased by 55.3% from 2002 to 2024.
- Older age and higher illness severity were the strongest predictors of mortality.
- Neurological conditions and comorbidities also significantly increased mortality risk.

## Abstract

There is much focus on the management of the acute emergency medical admission; however, comparative outcome data over long time periods are sparse.

We report all the outcomes of emergency admissions over 23 years (2002–2024).

Demographic and clinical details are described. Predictors of 30-day in-hospital mortality were analysed with logistic and Cox regression.

The 2002–2024 cohort consisted of 186,004 admissions in 95,192 patients. The 30-day in-hospital mortality per admission averaged 3.8% (95% CI 3.7% to 3.9%); there was a relative risk reduction (RRR) between 2002 and 2024 of 55.3%, from 5.5% to 2.4% (p = 0.001), with a calculated number needed to treat (NNT) of 33. Per patient mortality (single admission only considered; last admission if > 1) averaged 7.5% (95% CI 7.4% to 7.7%); there was a RRR of 77.9% between 2002 and 2024, from 13.1% to 2.9% (p = 0.001) with NNT of 9.9. Total in-hospital deaths were 14,092 at respective age for males of 73.6 (SEM 0.12) and females of 79.4 (SEM 0.11). The strongest predictors of short-term 30-day in-hospital mortality were being older (> 70 years)—OR 2.05 (95%CI 1.94, 2.18) and the acute illness severity score 1.91 (95%CI 1.85, 1.96). Other predictors were the Charlson Index 1.32 (95% CI 1.28, 1.37) and a primary neurological MDC (major disease category) 1.18 (95% CI 1.09, 1.27).

The 30-day in-hospital mortality for emergency medical admissions has improved over time.

## Full-text entities

- **Diseases:** MDC (MESH:D004830), deaths (MESH:D003643)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC12578694/full.md

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Source: https://tomesphere.com/paper/PMC12578694