# A Headache and an Abscess: A Case of Cerebral Toxoplasmosis

**Authors:** Muhammad Ghazi Khan, Alex James Francis Fischer, Makenzie Dye, Rebekah Lantz

PMC · DOI: 10.7759/cureus.93678 · Cureus · 2025-10-01

## TL;DR

This paper presents a case of cerebral toxoplasmosis in an immunocompromised patient, highlighting the importance of thorough diagnosis and multidisciplinary care.

## Contribution

The novelty lies in the detailed clinical presentation and management of a rare case of cerebral toxoplasmosis in an HIV-positive patient.

## Key findings

- Ring-enhancing brain lesions were identified through imaging in a 51-year-old Haitian woman.
- The patient's immunocompromised state was attributed to a newly diagnosed HIV infection.
- Multidisciplinary care and an interpreter were essential for effective diagnosis and treatment.

## Abstract

Cerebral toxoplasmosis is a rare cause of brain abscesses, but it occurs more commonly in immunocompromised individuals. Prompt diagnosis and treatment can minimize associated neurologic mortality. When a patient presents with vague symptoms, it is important to continue gathering the patient's medical history and perform a thorough workup. This report describes a case of a 51-year-old Haitian woman who presented with seizure-like activity. Brain imaging revealed ring-enhancing lesions, leading to a new diagnosis of human immunodeficiency virus (HIV) as the cause of her immunocompromised state. Her care necessitated an interpreter, as well as a multidisciplinary team of specialists to diagnose, treat, and provide the best care.

## Linked entities

- **Diseases:** cerebral toxoplasmosis (MONDO:0005697)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** Cerebral Toxoplasmosis (MESH:D016781), Headache (MESH:D006261), brain abscesses (MESH:D001922), seizure (MESH:D012640)
- **Species:** Human immunodeficiency virus (species) [taxon 12721], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12578651/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12578651/full.md

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Source: https://tomesphere.com/paper/PMC12578651