# Dimethylsulfoxide-Associated Anaphylaxis in Autologous Stem Cell Transplantation: A Case Report

**Authors:** Didar Yanardag Acik, Elif Suyani, Bilal Aygun

PMC · DOI: 10.1155/carm/9351610 · Case Reports in Medicine · 2025-10-24

## TL;DR

A patient experienced anaphylaxis from dimethylsulfoxide during stem cell thawing, highlighting a rare but serious side effect.

## Contribution

This case report documents anaphylaxis caused by DMSO in stem cell transplantation, emphasizing clinical awareness.

## Key findings

- Anaphylaxis occurred in a patient after DMSO exposure during stem cell thawing.
- The patient was successfully managed with standard anaphylaxis treatment protocols.

## Abstract

Dimethylsulfoxide (DMSO) is often used for freezing hematopoietic stem cells. DMSO is associated with mild side effects and rarely serious side effects such as anaphylaxis. We present a patient with acute anaphylaxis after DMSO and patient management.

## Linked entities

- **Chemicals:** dimethylsulfoxide (PubChem CID 679), DMSO (PubChem CID 679)

## Full-text entities

- **Diseases:** Anaphylaxis (MESH:D000707)
- **Chemicals:** DMSO (MESH:D004121)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12578551/full.md

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Source: https://tomesphere.com/paper/PMC12578551