# Unmasking a Cerebral Arteriovenous Malformation Presenting as a Chronic Migraine-Type Headache at a District General Hospital

**Authors:** Kawser Ahmed, Anirban Deb Tanmoy, Hannah Aouad, Ashfaq Hamid

PMC · DOI: 10.7759/cureus.94936 · Cureus · 2025-10-19

## TL;DR

A woman with a severe, unresponsive migraine was found to have a rare brain abnormality, highlighting the need for imaging and specialist care.

## Contribution

This case emphasizes the importance of neuroimaging and collaboration in diagnosing atypical migraine-like presentations.

## Key findings

- Neuroimaging revealed a large, unruptured AVM in the left parieto-occipital region.
- Symptoms resolved after radiosurgery, confirming the AVM as the underlying cause.
- Early detection through imaging and specialist referral improved patient outcomes.

## Abstract

A female in her 50s was referred by her General Practitioner (GP) to our Same Day Emergency Care (SDEC) unit due to an unresponsive migraine attack. Associated features included nausea, photophobia, phonophobia, intermittent visual aura, and unintentional weight loss over the last two weeks. Arteriovenous malformations (AVMs) are rare vascular anomalies, with a prevalence of approximately 18 per 100,000 individuals. Although often asymptomatic, they may present atypically with migraine-like headaches, posing a diagnostic challenge.

Her full neurological assessment, including cranial nerves, cerebellar function, and motor and sensory systems, was unremarkable. However, neuroimaging revealed a large, unruptured, complex AVM in the left parieto-occipital region, associated with cerebral oedema and midline shift. Computed tomography angiography (CTA) and magnetic resonance angiography (MRA) confirmed a Spetzler-Martin Grade III AVM.

Her imaging was urgently discussed with the Neurosurgery Department at Oxford University Hospitals for further intervention, as our institution does not have a neurosurgery department being a district general hospital. The multidisciplinary team (MDT) recommended radiosurgery, and her symptoms resolved after the intervention.

This case illustrates the importance of neuroimaging in patients with refractory or unresponsive migraine, enabling early detection of serious intracranial pathology such as AVMs. It also highlights the value of timely specialist referral, inter-hospital collaboration, and patient-centred care in optimising outcomes.

## Linked entities

- **Diseases:** migraine (MONDO:0005277)

## Full-text entities

- **Diseases:** phonophobia (MESH:D012001), weight loss (MESH:D015431), Headache (MESH:D006261), nausea (MESH:D009325), AVMs (MESH:D001165), photophobia (MESH:D020795), vascular anomalies (MESH:D020785), cerebral oedema (MESH:D001929), Chronic Migraine (MESH:D008881), AVM (MESH:D002538)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12578465/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12578465/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12578465/full.md

---
Source: https://tomesphere.com/paper/PMC12578465