# Revolutionizing bladder tumor treatment with non-thermal atmospheric plasma treatment under local anesthesia: a case report

**Authors:** Dolev Perez, David Dothan, Boris Chertin

PMC · DOI: 10.1093/jscr/rjaf863 · Journal of Surgical Case Reports · 2025-10-31

## TL;DR

A new non-thermal plasma treatment for bladder cancer can be done with local anesthesia, avoiding general anesthesia risks.

## Contribution

Demonstration that non-thermal plasma treatment for bladder tumors can be performed under local anesthesia.

## Key findings

- Non-thermal atmospheric plasma can safely ablate superficial bladder tumors.
- The procedure can be performed under local anesthesia instead of general anesthesia.
- This approach may reduce anesthesia-related risks and improve patient quality of life.

## Abstract

Non-muscle-invasive bladder cancer exhibits low progression risk with high recurrence rate. Standard resection requires general anesthesia and carries inherent risks. CAPS Medical™ PlasmaSure™ is an innovative system that employs non-thermal atmospheric plasma in a minimally invasive procedure, and a first-in-human study has previously demonstrated its ability to safely and efficiently ablate superficial bladder tumors. The current case report shows that the same procedure can be conducted without the need for general anesthesia. These findings highlight a future potential for PlasmaSure™ to enable in-office efficient ablation of superficial bladder tumors, thereby minimizing anesthesia-related risks and enhancing patient quality of life.

## Linked entities

- **Diseases:** bladder cancer (MONDO:0004986)

## Full-text entities

- **Diseases:** bladder cancer (MESH:D001749), invasive (MESH:D009361)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12578273/full.md

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Source: https://tomesphere.com/paper/PMC12578273