# New formulation and valid inequalities for a periodic capacitated vehicle routing problem with multiple depots, heterogeneous fleet, and hard time-windows

**Authors:** Alejandro Arenas-Vasco, Juan Carlos Rivera, Maria Gulnara Baldoquín

PMC · DOI: 10.1371/journal.pone.0335389 · PLOS One · 2025-10-31

## TL;DR

This paper introduces a new and efficient method for solving a complex vehicle routing problem with multiple depots and time windows, inspired by a real-world vending machine industry challenge.

## Contribution

A novel formulation using continuous variables and depot replication improves model simplicity and computational efficiency.

## Key findings

- The new formulation outperforms previous approaches in computational experiments.
- It achieves optimality for small instances and reduces optimality gaps for medium-sized problems.
- The method shows faster solution times for finding feasible solutions.

## Abstract

This paper presents a new formulation and valid constraints for a periodic capacitated vehicle routing problem with multiple depots, heterogeneous fleet, and hard time-windows (MDHFPCVRP-TW). The problem raises from a real-world application in the vending machine industry in Medellín, Colombia. Our main contribution is a novel formulation that replaces binary depot-client assignment variables with continuous auxiliary variables and implements depot replication, achieving both model simplicity and computational efficiency. We introduce preprocessing techniques and valid constraints, particularly focusing on capacity-based constraints with client combinations, which significantly strengthen the formulation’s linear relaxation. Computational experiments demonstrate that our formulation consistently outperforms previous approaches across different instance sizes, achieving optimality for small instances and maintaining single-digit optimality gaps for medium-sized instances where earlier formulations showed gaps above 12%. The formulation shows particularly strong performance in solution time, often requiring less time to find feasible solutions. While limitations persist for very large instances, our results suggest promising directions for developing hybrid exact-heuristic methods for industrial-scale problems.

## Full-text entities

- **Genes:** NPY4R (neuropeptide Y receptor Y4) [NCBI Gene 5540] {aka NPY4-R, PP1, PPYR1, Y4}, THBS1 (thrombospondin 1) [NCBI Gene 7057] {aka THBS, THBS-1, TSP, TSP-1, TSP1}
- **Diseases:** MILP (MESH:D060085)
- **Chemicals:** 3IF (-)

## Full text

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## Figures

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12578217/full.md

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Source: https://tomesphere.com/paper/PMC12578217