# Successful Management of Recurrent Rectal Leiomyosarcoma: A Case Report

**Authors:** Annmarie Butare, Warqaa Akram

PMC · DOI: 10.1002/ccr3.71279 · 2025-10-30

## TL;DR

This case report describes a successful treatment for a rare and aggressive rectal tumor using radiation and surgery.

## Contribution

The paper presents a successful clinical case of rectal leiomyosarcoma management using a specific treatment sequence.

## Key findings

- Neoadjuvant radiation followed by total mesorectal excision achieved a disease-free state.
- The case demonstrates that a combination of therapies can lead to positive outcomes in rare rectal tumors.

## Abstract

Rectal leiomyosarcoma is rare and portends a poor prognosis with high recurrence rates. While no current gold‐standard treatment exists for rectal leiomyosarcoma, a disease‐free state can be successfully achieved with neoadjuvant radiation followed by total mesorectal excision.

## Linked entities

- **Diseases:** rectal leiomyosarcoma (MONDO:0003379)

## Full-text entities

- **Diseases:** Rectal Leiomyosarcoma (MESH:D007890)

## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12575435/full.md

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Source: https://tomesphere.com/paper/PMC12575435