Genomics reveals multiple introductions of the seventh pandemic Vibrio cholerae O1 El Tor lineage into Iran since 1965
Bita Bakhshi, Elisabeth Njamkepo, Mozhgan Derakhshan-Sefidi, Mohammad R. Pourshafie, Claire Jenkins, Caroline Rouard, François-Xavier Weill
TL;DR
Genomic analysis shows that cholera outbreaks in Iran since 1965 were caused by multiple introductions of a global strain from South Asia.
Contribution
The study reveals multiple introductions of the seventh pandemic Vibrio cholerae O1 El Tor lineage into Iran, rather than a single origin.
Findings
Multiple sublineages of the seventh pandemic Vibrio cholerae O1 El Tor lineage have caused cholera outbreaks in Iran.
The disease has been recurrently introduced from South Asia into Iran over time.
The incidence of cholera has declined significantly in Iran since 1965.
Abstract
Cholera epidemics due to Vibrio cholerae O1 El Tor have been occurring in Iran since 1965, but the incidence of this disease has declined significantly over time. We found that multiple sublineages of the seventh pandemic V. cholerae O1 El Tor lineage have caused cholera outbreaks in Iran, suggesting recurrent introductions of the disease from South Asia into Iran.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsVibrio bacteria research studies · Yersinia bacterium, plague, ectoparasites research · Bacillus and Francisella bacterial research