# Targeting ESM-1 inhibits spinal metastasis by disrupting tumor-endothelial adhesion

**Authors:** Seong Jun Kim, Wan-Kyu Ko, Daye Lee, Min Je Kim, Gi-Beom Ju, Zixiang Luo, Je-Beom Hong, Seung Hun Sheen, Seil Sohn

PMC · DOI: 10.1186/s43556-025-00332-0 · Molecular Biomedicine · 2025-10-30

## Full-text entities

- **Genes:** ESM1 (endothelial cell specific molecule 1) [NCBI Gene 11082] {aka endocan}
- **Diseases:** tumor (MESH:D009369), spinal metastasis (MESH:D009362)

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Source: https://tomesphere.com/paper/PMC12572558