# Efficacy of ultrasound guided venous cannulation positioning during venous-arterial extracorporeal membrane oxygenation

**Authors:** Yuanyuan Sun, Chengmin Huang, Weimei Ou, Zhixian Liu, Guangfeng Sun, Xinchen Zhang, Xu Chen, Bin Wang, Guoming Zhang

PMC · DOI: 10.3389/fcvm.2025.1656101 · Frontiers in Cardiovascular Medicine · 2025-10-16

## TL;DR

Using ultrasound to guide venous cannulation during VA-ECMO improves positioning accuracy and reduces complications, especially in non-CPR patients.

## Contribution

Demonstrates that ultrasound guidance during VA-ECMO cannulation improves clinical outcomes compared to conventional methods.

## Key findings

- Ultrasound-guided group had higher optimal cannula positioning rates and lower complications.
- Non-CPR patients in the ultrasound group had shorter ECMO duration and hospital stay.
- Ultrasound guidance was associated with reduced infection markers and improved survival trends.

## Abstract

To evaluate the clinical impact of ultrasound-guided venous cannulation positioning during the initiation of venous-arterial extracorporeal membrane oxygenation (VA-ECMO).

This retrospective study included 48 patients who received bedside VA-ECMO support between June 2019 and August 2024. Patients were divided into an ultrasound-guided group (UG, n = 23) and conventional body surface landmark group (BSL, n = 25). Clinical outcomes, cannula positioning accuracy, complications, infection markers, and prognosis were compared. A subgroup analysis was performed in patients who did not undergo cardiopulmonary resuscitation (non-CPR).

Compared to BSL group, patients in the UG group had significantly higher rates of optimal venous cannula positioning (p < 0.01), lower incidence of unstable flow and pulmonary edema, and shorter aortic valve closure time, infection markers (WBC, PCT) were also significantly lower in the UG group (p < 0.05). In the non-CPR subgroup, the UG group had shorter ECMO duration, hospital stay, and dual antibiotic therapy duration (all p < 0.05), with non-significant trends toward better survival.

Ultrasound-guided venous cannulation improves cannula positioning accuracy, reduces early complications, and may enhance clinical outcomes, particularly in non-CPR patients. Routine use of ultrasound guidance is thus recommended in bedside VA-ECMO procedures.

## Full-text entities

- **Diseases:** pulmonary edema (MESH:D011654), infection (MESH:D007239)
- **Chemicals:** VA (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC12571855/full.md

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Source: https://tomesphere.com/paper/PMC12571855