# Kawasaki disease complicated with shock syndrome and macrophage activation syndrome in children: a case report

**Authors:** Juxia Shu, Jingwei Sun, Jiachen Li, Mengjin Wang, Nan Dong, Dong Qi, Fang Liu

PMC · DOI: 10.3389/fped.2025.1675460 · Frontiers in Pediatrics · 2025-10-16

## TL;DR

This case report describes a rare instance of Kawasaki disease in a child complicated by shock syndrome and macrophage activation syndrome.

## Contribution

The novelty lies in the detailed documentation of a rare complication where KD is accompanied by both shock syndrome and MAS.

## Key findings

- KD complicated by shock syndrome and MAS is extremely rare in children.
- The case highlights the importance of early diagnosis and treatment in managing such complex presentations.

## Abstract

Kawasaki disease (KD) is an acute self-limited vasculitis of unknown etiology. Clinically, a small proportion of patients may develop shock syndrome or macrophage activation syndrome (MAS); however, KD shock syndrome (KDSS) complicated by MAS is extremely rare. This article provides a detailed report on the clinical diagnosis and treatment course of a child with KD complicated by KDSS and MAS.

## Linked entities

- **Diseases:** Kawasaki disease (MONDO:0012727), macrophage activation syndrome (MONDO:0015545)

## Full-text entities

- **Diseases:** shock syndrome (MESH:D012769), KD (MESH:D009080), vasculitis (MESH:D014657), MAS (MESH:D055501)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12571767/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12571767/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12571767/full.md

---
Source: https://tomesphere.com/paper/PMC12571767