# Electrical impedance tomography to guide mechanical ventilation for asymmetrical lung injury: a case report

**Authors:** Albina Musaj, Louis Tronchet, Corstiaan den Uil, Dolf Weller

PMC · DOI: 10.3389/fmed.2025.1675679 · Frontiers in Medicine · 2025-10-16

## TL;DR

A 66-year-old woman with severe one-sided lung injury was successfully managed using personalized ventilation settings guided by electrical impedance tomography.

## Contribution

Demonstrates the use of EIT and esophageal pressure measurements for individualized PEEP titration in asymmetrical lung injury.

## Key findings

- High PEEP levels (18 cmH2O) were initially optimal for alveolar recruitment.
- PEEP levels were successfully reduced to 8 cmH2O as the lung recovered, leading to extubation.
- EIT-based monitoring helped prevent overdistension while optimizing ventilation.

## Abstract

During last years, new methods of advanced ventilatory monitoring have been introduced to implement lung-protective ventilation. We present a unique case of a 66-year-old female admitted to the ICU with severe unilateral lung injury due to COVID-19 pneumococcal superinfection. By combining electrical impedance tomography (EIT) and esophageal pressure measurements, individualized positive end-expiratory pressure (PEEP) titration was performed. Initially, high PEEP levels (18 cmH2O) were optimal. Over the course of a week, reflecting dynamic lung recovery, PEEP levels could be reduced to 8 cmH2O followed by extubation. This case emphasizes the importance of personalized PEEP titration in managing asymmetric lung injury, highlighting how EIT-based monitoring can optimize alveolar recruitment while minimizing overdistension.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382), pneumococcal superinfection (MESH:D015163), lung injury (MESH:D055370)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12571728/full.md

## References

28 references — full list in the complete paper: https://tomesphere.com/paper/PMC12571728/full.md

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Source: https://tomesphere.com/paper/PMC12571728