# Knowledge, Attitudes, and Practices of Dermatologists on Chronic Pruritus and Its Management

**Authors:** Ankur Talwar, Shikha Shivhare, Devesh K Joshi, Monil Gala, Snehal S Muchhala, Seema V Bhagat, Arti Sanghavi, Sagar Katare, Bhavesh P Kotak

PMC · DOI: 10.7759/cureus.93494 · Cureus · 2025-09-29

## TL;DR

This study explores how dermatologists in India understand and manage chronic itching, focusing on their use of antihistamines and patient care approaches.

## Contribution

The study provides insights into dermatologists' knowledge, attitudes, and practices regarding chronic pruritus management in India.

## Key findings

- Dermatologists recognize histamine and H1 receptors as key in chronic pruritus pathophysiology.
- Many dermatologists prefer once-daily antihistamine regimens for better adherence and symptom control.
- Patient education and safety data for high-risk groups are identified as critical needs.

## Abstract

Background

Chronic pruritus (CP) is a prevalent and distressing condition with a significant impact on patients' quality of life. Despite advances in understanding its pathophysiology, management remains challenging, necessitating insights into dermatologists' perspectives on CP treatment.

Objective

This study aimed to assess the knowledge, attitudes, and practices (KAP) of dermatologists regarding CP management, with a focus on antihistamine use.

Methods

A cross-sectional study was conducted among dermatologists across India. A total of 220 participants completed the quantitative KAP questionnaire, while 15 (6.82%) underwent qualitative interviews. Data were analyzed using descriptive statistics and thematic analysis.

Results

Dermatologists showed good knowledge of CP pathophysiology, with histamine and H1 receptors recognized as key mediators. Antihistamines were widely used, and many respondents reported a shift toward once-daily regimens to improve symptom control and adherence. Patient education was identified as a critical need, alongside further safety and efficacy data in high-risk groups.

Conclusion

Dermatologists emphasized a patient-centered approach, prioritizing the identification of underlying causes while addressing symptoms. Hydroxyzine and its sustained-release formulation were regarded as convenient and effective, supporting simplified dosing and better adherence. Strengthening patient education remains essential to optimizing CP management.

## Linked entities

- **Chemicals:** histamine (PubChem CID 774), Hydroxyzine (PubChem CID 3658)

## Full-text entities

- **Diseases:** CP (MESH:D011537)
- **Chemicals:** histamine (MESH:D006632), Hydroxyzine (MESH:D006919)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

10 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12571696/full.md

## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC12571696/full.md

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Source: https://tomesphere.com/paper/PMC12571696