# Sleep quality and levels of stress, anxiety, and depression in patients treated with homeopathy: a prospective study in the Brazilian public healthcare service

**Authors:** Fernanda Maria Simões da Costa Fujino, Ana Paula Ribeiro, Denise Castanho Antunes, Renato Jimenez Gomez, Guilherme Eustáquio Furtado, Patrícia Colombo-Souza

PMC · DOI: 10.1590/1516-3180.2025.3033.06082025 · São Paulo Medical Journal · 2025-10-27

## TL;DR

This study shows that homeopathic treatment improved sleep quality and reduced stress, anxiety, and depression in patients over six months.

## Contribution

The study provides empirical evidence of homeopathy's effectiveness in improving mental health and sleep in a public healthcare setting.

## Key findings

- Homeopathic treatment significantly improved sleep quality and reduced stress, anxiety, and depression.
- Sleep quality and anxiety were strongly correlated with stress levels.
- The results suggest homeopathy may help prevent chronic noncommunicable diseases.

## Abstract

Chronic noncommunicable diseases (NCDs) have a multifactorial etiology and are associated with psychosocial factors, such as stress, anxiety, and depression. Sleep quality also influences general health and is associated with obesity and NCDs. Homeopathy, as a medical specialty, is effective in managing these conditions because of its comprehensive approach to individuals.

To evaluate the influence of homeopathic treatment on sleep quality and levels of stress, anxiety, and depression.

Observational, longitudinal, and prospective study on individuals over 18 years of age with homeopathic medical follow-up for 6 months in the public healthcare service of Guarulhos, São Paulo.

Participants were evaluated initially (T0) and after 3 (T1) and 6 months (T2) using validated questionnaires (Pittsburgh Sleep Quality Index and the Depression Anxiety and Stress Scale), following all ethical precepts. The scores were compared over time and correlated with each other (P < 0.05).

The mean patient age was 49 years. Initially, 81% of the participants had sleep disorders and severe or extremely severe levels of stress (33.78%), anxiety (28.38%), and depression (27.03%). A total of 26 patients were present at the three evaluation points, which were included as the participants of the study. Homeopathic treatment significantly improved sleep quality and reduced stress, anxiety, and depression. Sleep quality and anxiety were strongly (r = 0.53, P = 0.005) and weakly (r = 0.25, P = 0.021) correlated with stress, respectively.

In the short term, homeopathic treatment had a positive impact on the sample, suggesting that this therapy can be used to prevent NCDs.

## Linked entities

- **Diseases:** anxiety (MONDO:0005618), depression (MONDO:0002050)

## Full-text entities

- **Diseases:** depression (MESH:D003866), Chronic noncommunicable diseases (MESH:D000073296), Depression Anxiety (MESH:D001007), sleep disorders (MESH:D012893), obesity (MESH:D009765)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12571486/full.md

## References

30 references — full list in the complete paper: https://tomesphere.com/paper/PMC12571486/full.md

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Source: https://tomesphere.com/paper/PMC12571486