# The autoactivity of tomato helper NLR immune proteins of the NRC clade is unaltered in Nicotiana benthamiana prf mutants

## TL;DR

This paper shows that tomato NRC clade immune proteins can trigger cell death independently in Nicotiana benthamiana prf mutants.

## Contribution

It demonstrates that autoactivity of NRC clade proteins is not affected by prf mutations in Nicotiana benthamiana.

## Key findings

- Tomato NRC clade proteins trigger hypersensitive cell death without sensor partners.
- Autoactivity remains unchanged in Nicotiana benthamiana prf mutants.
- NRC clade function is independent of prf in this system.

## Abstract

Nucleotide-binding and leucine-rich repeat immune receptors of the NRC clade act in one direction, with autoactive helpers able to trigger hypersensitive cell death without their sensor partners.