# Multifocal Biliary Adenoma Involving the Gallbladder and Common Bile Duct Presenting With Obstructive Jaundice: A Case Report

**Authors:** Austin Guadarrama, Tyler Mouw, Edwin O Onkendi, Mohamad Sidani, Kanak Das, Luis Brandi

PMC · DOI: 10.7759/cureus.93487 · Cureus · 2025-09-29

## TL;DR

A rare case of multifocal biliary adenoma presented as jaundice in a 70-year-old man, requiring surgery to prevent cancer progression.

## Contribution

This case report highlights a rare presentation of multifocal biliary adenoma mimicking malignancy and emphasizes the need for surgical intervention.

## Key findings

- Multifocal biliary adenoma can present with obstructive jaundice, mimicking invasive cancer.
- Surgical resection is curative and prevents progression to carcinoma.
- Histopathology confirmed the presence of tubulovillous adenoma without invasive malignancy.

## Abstract

Biliary adenomas are rare neoplastic processes of the gallbladder and extrahepatic biliary tree that are pre-malignant. These tumors infrequently present with obstructive jaundice, which is more suggestive of underlying invasive malignancy. Here, we present a case of multifocal biliary adenoma without invasive cancer in a 70-year-old man who presented with jaundice. Initial laboratory results and imaging suggested a malignant process, prompting surgical resection. Intraoperative findings and histopathologic examination revealed a multifocal tubulovillous adenoma involving the gallbladder and distal common bile duct. The patient ultimately underwent a curative pancreatoduodenectomy procedure. This case demonstrates multifocal biliary adenoma presenting as jaundice without underlying malignancy. Surgical treatment is necessary to relieve symptoms and prevent the progression to carcinoma.

## Linked entities

- **Diseases:** obstructive jaundice (MONDO:0006874), carcinoma (MONDO:0004993)

## Full-text entities

- **Diseases:** jaundice (MESH:D007565), cancer (MESH:D009369), Obstructive Jaundice (MESH:D041781), Biliary Adenoma (MESH:D000236)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12571022/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12571022/full.md

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Source: https://tomesphere.com/paper/PMC12571022