# Beyond Pathology: A Procedure-Based Approach to Planning and Predicting Outcomes in Robotic Gynaecological Oncology Surgery

**Authors:** Mohamed Abdelwanis Mohamed Abdelaziz, Ayodele Olaleye, Khaled Sabrah, Ahmed Mohamed, Moustafa Fayad, Ketankumar Gajjar

PMC · DOI: 10.1186/s12893-025-03217-9 · BMC Surgery · 2025-10-28

## TL;DR

This study shows that planning robotic gynecological surgery based on procedural needs, rather than just pathology, better predicts operating time and outcomes.

## Contribution

A novel framework for surgical planning based on procedural requirements rather than traditional pathology markers is proposed.

## Key findings

- Procedural requirements like lymphadenectomy and adhesiolysis better predict operating time than traditional markers like BMI or pathology type.
- The study found a significant decrease in operating time and intraoperative complications over the study period despite similar case complexity.
- All complications were minor (Clavien-Dindo Grade I-II), supporting the feasibility of robotic surgery in complex cases.

## Abstract

Current surgical planning in robotic gynaecology relies heavily on pathological diagnosis, yet operating theatre utilisation may depend more on procedural requirements. Recent advances in machine learning-based surgical prediction have highlighted the need for more accurate planning models whilst challenging fundamental assumptions about surgical complexity.

To compare the impact of procedural requirements versus traditional complexity markers on operating time and complications in robotic gynaecological surgery, and to develop a practical framework for procedure-based surgical planning that could complement contemporary machine learning approaches.

Retrospective analysis of 80 consecutive robotic gynaecological surgeries (2021–2024) at a single tertiary centre. We examined relationships between procedural requirements (lymphadenectomy, adhesiolysis), traditional complexity markers (BMI > 35, pathology type, previous surgery), and outcomes (operating time, complications). A Preoperative Procedural Demand Score (PPDS) was developed and validated against pathology-based predictions. Multivariable regression analysis included β-coefficients, confidence intervals, and comprehensive model diagnostics.

Procedural requirements explained operating time variation better than pathology type. Standard procedures averaged 135.4 ± 28.6 min. Adding lymphadenectomy increased time by 33.1 min (95% CI: 24.8–41.4), adhesiolysis by 19.8 min (95% CI: 11.5–28.1). Traditional complexity markers showed minimal impact: BMI > 35 added 8.1 min (95% CI: -7.2 to 23.4, p = 0.42), previous surgery 7.6 min (95% CI: -8.4 to 23.6, p = 0.48). All complications (6.3%) were minor (Clavien-Dindo Grade I-II). Operating time decreased from 178.0 ± 47.2 to 135.9 ± 36.8 min between study halves (p < 0.001), whilst intraoperative complications decreased from 12.5 to 0% (p = 0.02), despite similar case complexity.

This study demonstrates that procedural requirements better predict operating time than traditional markers in robotic gynaecological surgery, representing a novel conceptual framework for surgical planning. However, the single-centre design and modest predictive accuracy compared to contemporary machine learning approaches indicate that comprehensive multi-centre prospective validation is essential before recommending widespread adoption. The excellent safety profile across all complexity levels supports the feasibility of robotic surgery in traditionally “complex” cases, though larger studies are needed to establish definitive safety parameters.

## Full-text entities

- **Genes:** TRH (thyrotropin releasing hormone) [NCBI Gene 7200] {aka Pro-TRH, TRF}
- **Diseases:** VAIN 3 (MESH:C537153), adhesions (MESH:D000267), Urinary Tract Infection (MESH:D014552), malignancy (MESH:D009369), urinary retention (MESH:D016055), fatigue (MESH:D005221), Vaginal Intraepithelial Neoplasia (MESH:D002578), hypertension (MESH:D006973), endometrial pathology (MESH:D014591), hyperplasia (MESH:D006965), bladder injury (MESH:D001745), PPDS (MESH:D000073818), Serosal injuries (MESH:D012700), serosa tear (MESH:D012167), obese (MESH:D009765), renal disease (MESH:D007674), cardiac disease (MESH:D006331), endometrial cancer (MESH:D016889), ovarian pathology (MESH:D010049), endometrial and ovarian pathologies (MESH:D000077216), menorrhagia (MESH:D008595), chronic pelvic pain (MESH:D011472), tremor (MESH:D014202), benign disease (MESH:D004194), respiratory disease (MESH:D012140), chest infection (MESH:D002637), cervical cancer (MESH:D002583), complication (MESH:D008107), diabetes (MESH:D003920)
- **Chemicals:** BSO (MESH:D019328), HDU (MESH:C001965)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12570587/full.md

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Source: https://tomesphere.com/paper/PMC12570587