# Anti-inflammatory and antioxidant properties of six common fruit extracts: An in vitro study

**Authors:** Sujata Chhabile, Arun Dodamani, Prashanth Vishwakarma, Harish Jadav, Ankita Gadekar, Snehal Chintale

PMC · DOI: 10.6026/973206300211986 · Bioinformation · 2025-07-31

## TL;DR

This study examines the antioxidant and anti-inflammatory effects of six common fruits in a lab setting.

## Contribution

The study provides new in vitro evidence on the anti-inflammatory and antioxidant potential of six fruit extracts.

## Key findings

- Antioxidant activity of fruit extracts was concentration-dependent and statistically significant.
- Anti-inflammatory effects were observed but were less potent than the standard drug diclofenac.
- Fruit extracts show potential for managing oxidative stress and inflammation.

## Abstract

Fruits like ananas comosus, Malus pumila and Manilkara zapota are known to have
antioxidant activity in vitro, while Mangifera indica and M. pumila have moderate
anti-inflammatory effects. Extracts were tested at 10-50 µL and compared with standard drugs. Antioxidant activity was
concentration-dependent and statistically significant (p ≤ 0.05). Anti-inflammatory activity, though notable, was less than diclofenac.
Thus, the potential of fruit extracts in managing oxidative stress and inflammation is reported.

## Linked entities

- **Species:** Ananas comosus (taxon 4615), Malus pumila (taxon 283210), Manilkara zapota (taxon 3741), Mangifera indica (taxon 29780)

## Full-text entities

- **Diseases:** inflammation (MESH:D007249)
- **Chemicals:** fruit extracts (-), diclofenac (MESH:D004008)
- **Species:** Malus pumila (paradise apple, species) [taxon 283210], Ananas comosus (pineapple, species) [taxon 4615], Mangifera indica (mango, species) [taxon 29780], Manilkara zapota (sapodilla, species) [taxon 3741]

## Full text

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## References

27 references — full list in the complete paper: https://tomesphere.com/paper/PMC12569944/full.md

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Source: https://tomesphere.com/paper/PMC12569944