# Electrocardiographic and biochemical profile of acute coronary syndrome in hospitalized COVID-19 patients

**Authors:** Sandeep Aharwar, Rajat Kumar Tuteja, Pushpendra Singh Sengar, Dhruv Chowda

PMC · DOI: 10.6026/973206300212065 · Bioinformation · 2025-07-31

## TL;DR

This study finds that a significant portion of hospitalized COVID-19 patients experience acute coronary syndromes, with older and those with diabetes or hypertension being most affected.

## Contribution

The study provides empirical evidence on the electrocardiographic and biochemical profile of acute coronary syndromes in hospitalized COVID-19 patients.

## Key findings

- 26% of hospitalized COVID-19 patients had ECG-confirmed acute coronary syndromes.
- Older patients, diabetics, and those with hypertension showed higher rates of elevated inflammatory and cardiac biomarkers.
- STEMI was strongly associated with age over 60 and increased mortality.

## Abstract

COVID-19 has been associated with the occurrence of acute coronary syndromes (ACS) and the medical and scientific communities
consider the virus to put acute coronary syndromes (ACS) at risk because of its inflammatory and thrombotic effects. In a cross-sectional
study of 100 hospitalized patients with COVID-19, 26 percent had ECG-confirmed ACS (16 percent STEMI/10 percent NSTEMI). The highest
rates of elevated inflammatory and cardiac biomarkers occurred among older people, as well as diabetic and hypertensive patients. STEMI
was substantially correlated to age >60 and increased fatality. It has become vital to detect cardiac involvement of COVID-19 at an
early stage to diminish negative outcomes.

## Linked entities

- **Diseases:** acute coronary syndromes (MONDO:0005542), diabetes (MONDO:0005015), COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382), thrombotic (MESH:D013927), NSTEMI (MESH:D000072658), STEMI (MESH:D000072657), diabetic (MESH:D003920), cardiac (MESH:D006331), hypertensive (MESH:D006973), ACS (MESH:D054058), inflammatory (MESH:D007249)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12569938/full.md

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Source: https://tomesphere.com/paper/PMC12569938