# A review on impact of adipocytokines in post postmenopausal women

## TL;DR

This review discusses how hormones and proteins like ghrelin, leptin, and adiponectin affect weight and metabolism in postmenopausal women.

## Contribution

The paper provides a comprehensive overview of adipocytokines' roles in postmenopausal weight regulation.

## Key findings

- Estrogen decline post-menopause leads to fat accumulation and insulin resistance.
- Low adiponectin and disrupted leptin-ghrelin signaling are associated with higher BMI.
- Vitamin D and lifestyle changes may help manage weight in postmenopausal women.

## Abstract

Obesity in postmenopausal women is a major global health concern due to hormonal and metabolic changes. This review explores the
roles of ghrelin, leptin, adiponectin, insulin, AMPK, and vitamin D in energy regulation and weight fluctuation. Estrogen decline
post-menopause alters metabolic balance, contributing to fat accumulation and insulin resistance. Reduced adiponectin and disrupted
leptin-ghrelin signalling are linked with increased body mass index. Vitamin D sufficiency, alongside lifestyle changes, may support
weight management in this population.