# Prevalence and risk factors of subclinical hypothyroidism in postmenopausal women: A cross-sectional study

**Authors:** Chakresh Jain, Nishi Mishra, Sarita Singh, Arunendra Nirat

PMC · DOI: 10.6026/973206300212241 · Bioinformation · 2025-07-31

## TL;DR

This study finds that nearly a quarter of postmenopausal women have subclinical hypothyroidism, with risk factors like higher BMI and hypertension.

## Contribution

The study identifies specific risk factors and prevalence of subclinical hypothyroidism in postmenopausal women.

## Key findings

- Subclinical hypothyroidism was found in 22.5% of postmenopausal women.
- Higher BMI, dyslipidemia, and hypertension are significantly associated with thyroid dysfunction.
- Thyroid dysfunction was more common in women within 5-10 years of menopause.

## Abstract

The prevalence and associated risk factors of subclinical hypothyroidism among 142 postmenopausal women aged 45-70 years. Thyroid
profiles were evaluated using serum TSH and free T4 levels, identifying subclinical hypothyroidism in 22.5% of participants. Higher BMI,
dyslipidemia, and hypertension showed significant associations with thyroid dysfunction. Subclinical hypothyroidism was more common
among women within 5-10 years of menopause. These findings underscore the need for routine thyroid screening in postmenopausal women.

## Linked entities

- **Diseases:** dyslipidemia (MONDO:0002525)

## Full-text entities

- **Diseases:** dyslipidemia (MESH:D050171), thyroid dysfunction (MESH:D013959), Subclinical hypothyroidism (MESH:D058345), hypertension (MESH:D006973)
- **Chemicals:** T4 (MESH:D013974)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12569926/full.md

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Source: https://tomesphere.com/paper/PMC12569926