# Clinical and radiographic comparison of sybograf® and ostin® in treating periodontal intrabony defects

**Authors:** Kaushal Pati Tripathi, Rohit Mishra, Varsha Choubey, Rajul Kaurav, Anshul Gulati, Arohi Aglawe

PMC · DOI: 10.6026/973206300211860 · Bioinformation · 2025-07-31

## TL;DR

This study compares two materials, Sybograf and Ostin, for treating periodontal defects, finding that Sybograf shows better clinical results in reducing pocket depth and improving bone regeneration.

## Contribution

The study provides a direct clinical and radiographic comparison of Sybograf and Ostin in treating periodontal intrabony defects.

## Key findings

- Sybograf showed a 72.4% reduction in probing pocket depth and 32.58% relative attachment level gain after 9 months.
- Sybograf demonstrated 33.1% bone fill compared to 25.5% with Ostin.
- Both materials were effective in bone regeneration, but Sybograf had superior clinical outcomes.

## Abstract

The capacity of Sybograf and Ostin to regenerate was compared in chronic periodontitis of three-wall vertical periodontitis defects.
The material was randomly given for 30 patients and the clinical and radiographic assessments done at the baseline and after 3, 6, and 9
months. Sybograf (R) produced more effect of PPD reduction (4.2 mm, 72.4%) and RAL gain (4.3 mm, 32.58%) when compared to Ostin (R ) at
9 months. There was no gross discrepancy between the intergroup bone fill (Sybograf there was bone fill) and (Ostin there was bone fill)
33.1 per cent and 25.5 per cent, respectively. Sybograf 2 characteristic showed superior clinical results and both substrates were
capable of regenerating bone efficiently.

## Linked entities

- **Diseases:** chronic periodontitis (MONDO:0005593)

## Full-text entities

- **Diseases:** periodontal intrabony defects (MESH:D010518), chronic periodontitis (MESH:D055113)
- **Chemicals:** RAL (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12569924/full.md

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Source: https://tomesphere.com/paper/PMC12569924